Gene Symbol: camk2b1
Description: calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1
Alias: CAMK2Gb, camk2b, fj90d04, si:dkey-174n20.2, wu:fj90d04, zgc:165373, calcium/calmodulin-dependent protein kinase type II subunit beta
Rothschild S, Lister J, Tombes R. Differential expression of CaMK-II genes during early zebrafish embryogenesis. Dev Dyn. 2007;236:295-305 pubmed
..At the time of somite formation, zygotic expression from six genes (camk2a1, camk2b1, camk2g1, camk2g2, camk2d1, camk2d2) results in a second phase of increased activity...
Rothschild S, Easley C, Francescatto L, Lister J, Garrity D, Tombes R. Tbx5-mediated expression of Ca(2+)/calmodulin-dependent protein kinase II is necessary for zebrafish cardiac and pectoral fin morphogenesis. Dev Biol. 2009;330:175-84 pubmed publisher
..Morphants of beta2 CaMK-II (camk2b2), but not the beta1 CaMK-II (camk2b1) paralog, exhibit bradycardia, elongated hearts and diminished pectoral fin development...
Zhong H, Zou H, Semenov M, Moshinsky D, He X, Huang H, et al
. Characterization and development of novel small-molecules inhibiting GSK3 and activating Wnt signaling. Mol Biosyst. 2009;5:1356-60 pubmed publisher
..Together, 3F8 and its derivatives could be useful as new reagents and potential therapeutic candidates for GSK3 related diseases. ..
Francescatto L, Rothschild S, Myers A, Tombes R. The activation of membrane targeted CaMK-II in the zebrafish Kupffer's vesicle is required for left-right asymmetry. Development. 2010;137:2753-62 pubmed publisher
Huang K, Chen G, Cheng C, Liao K, Hung C, Chang G, et al
. Phosphorylation of the zebrafish M6Ab at serine 263 contributes to filopodium formation in PC12 cells and neurite outgrowth in zebrafish embryos. PLoS ONE. 2011;6:e26461 pubmed publisher
..In the present study, we used the zebrafish as a model system to investigate the role of zebrafish M6Ab in filopodium formation in PC12 cells and neurite outgrowth in zebrafish embryos...
Roy B, Ferdous J, Ali D. NMDA receptors on zebrafish Mauthner cells require CaMKII-? for normal development. Dev Neurobiol. 2015;75:145-62 pubmed publisher
..Gene duplication in zebrafish has resulted in the occurrence of seven CaMKII genes (camk2a, camk2b1, camk2b2, camk2g1, camk2g2, camk2d1, and camk2d2) that are developmentally expressed...