Gene Symbol: ca15b
Description: carbonic anhydrase XVb
Alias: fd15c07, wu:fd15c07, wu:fi24f01, zgc:65797, zgc:77106, carbonic anhydrase XVb, carbonic anhydrase XV b, zCA15b
Lin T, Liao B, Horng J, Yan J, Hsiao C, Hwang P. Carbonic anhydrase 2-like a and 15a are involved in acid-base regulation and Na+ uptake in zebrafish H+-ATPase-rich cells. Am J Physiol Cell Physiol. 2008;294:C1250-60 pubmed publisher
..These results provide molecular physiological evidence to support the roles of these two zCA isoforms in Na+ uptake and acid-base regulation mechanisms in zebrafish HR cells. ..
Meyen D, Tarbashevich K, Banisch T, Wittwer C, Reichman Fried M, Maugis B, et al
. Dynamic filopodia are required for chemokine-dependent intracellular polarization during guided cell migration in vivo. elife. 2015;4: pubmed publisher
..Together, we show that filopodia allow the interpretation of the chemotactic gradient in vivo by directing single-cell polarization in response to the guidance cue. ..
Liu Y, Lin Z, Liu M, Wang H, Sun H. Overexpression of DYRK1A, a Down Syndrome Candidate gene, Impairs Primordial Germ Cells Maintenance and Migration in zebrafish. Sci Rep. 2017;7:15313 pubmed publisher
..Of note, ca15b and piwil1, two identified critical factors for PGCs development, showed ectopic expression induced by ..
Wang H, Teng Y, Xie Y, Wang B, Leng Y, Shu H, et al
. Characterization of the carbonic anhydrases 15b expressed in PGCs during early zebrafish development. Theriogenology. 2013;79:443-52 pubmed publisher
The main function of carbonic anhydrases is to regulate acid-base balance. In the present study, the zebrafish CA15b sequence was identified from the National Center for Biotechnology Information database (accession No. NM_213182)...
Tarbashevich K, Reichman Fried M, Grimaldi C, Raz E. Chemokine-Dependent pH Elevation at the Cell Front Sustains Polarity in Directionally Migrating Zebrafish Germ Cells. Curr Biol. 2015;25:1096-103 pubmed publisher
Hartwig J, Tarbashevich K, Seggewiß J, Stehling M, Bandemer J, Grimaldi C, et al
. Temporal control over the initiation of cell motility by a regulator of G-protein signaling. Proc Natl Acad Sci U S A. 2014;111:11389-94 pubmed publisher
Sumi K, Nou I, Kho K. Identification and expression of a novel carbonic anhydrase isozyme in the pufferfish Takifugu vermicularis. Gene. 2016;588:173-9 pubmed publisher
..Our results suggest that the pCAn isozyme might be related to CA IV-like isozymes. Further functional studies are needed to investigate the function of the pCAn isozyme in T. vermicularis. ..