Gene Symbol: ca14
Description: carbonic anhydrase XIV
Alias: zgc:123188, carbonic anhydrase 14
Lin T, Liao B, Horng J, Yan J, Hsiao C, Hwang P. Carbonic anhydrase 2-like a and 15a are involved in acid-base regulation and Na+ uptake in zebrafish H+-ATPase-rich cells. Am J Physiol Cell Physiol. 2008;294:C1250-60 pubmed publisher
..These results provide molecular physiological evidence to support the roles of these two zCA isoforms in Na+ uptake and acid-base regulation mechanisms in zebrafish HR cells. ..
Esbaugh A, Perry S, Gilmour K. Hypoxia-inducible carbonic anhydrase IX expression is insufficient to alleviate intracellular metabolic acidosis in the muscle of zebrafish, Danio rerio. Am J Physiol Regul Integr Comp Physiol. 2009;296:R150-60 pubmed publisher
Tarbashevich K, Reichman Fried M, Grimaldi C, Raz E. Chemokine-Dependent pH Elevation at the Cell Front Sustains Polarity in Directionally Migrating Zebrafish Germ Cells. Curr Biol. 2015;25:1096-103 pubmed publisher
Ito Y, Kobayashi S, Nakamura N, Miyagi H, Esaki M, Hoshijima K, et al
. Close Association of Carbonic Anhydrase (CA2a and CA15a), Na(+)/H(+) Exchanger (Nhe3b), and Ammonia Transporter Rhcg1 in Zebrafish Ionocytes Responsible for Na(+) Uptake. Front Physiol. 2013;4:59 pubmed publisher
..Our findings suggest that CA2a, CA15a, and Rhcg1 play a key role in Na(+)uptake under FW conditions by forming a transport metabolon with Nhe3b. ..
Matsumoto H, Fujiwara S, Miyagi H, Nakamura N, Shiga Y, Ohta T, et al
. Carbonic Anhydrase Inhibitors Induce Developmental Toxicity During Zebrafish Embryogenesis, Especially in the Inner Ear. Mar Biotechnol (NY). 2017;19:430-440 pubmed publisher
..Thus, our findings demonstrated the importance of potential risk assessment of CA inhibition, especially regarding the formation of otoliths as a one of the most sensitive organs in embryogenesis. ..
Patrikainen M, Tolvanen M, Aspatwar A, Barker H, Ortutay C, Jänis J, et al
. Identification and characterization of a novel zebrafish (Danio rerio) pentraxin-carbonic anhydrase. Peerj. 2017;5:e4128 pubmed publisher
..These findings provide novel insights into the evolution, structure, and function of this unique CA form. ..