Gene Symbol: brpf1
Description: bromodomain and PHD finger containing, 1
Alias: zgc:55530, peregrin
Torres Vazquez J, Gitler A, Fraser S, Berk J, Van N Pham -, Fishman M, et al
. Semaphorin-plexin signaling guides patterning of the developing vasculature. Dev Cell. 2004;7:117-23 pubmed
..These results reveal the fundamental conservation of repulsive patterning mechanisms between axonal migration in the central nervous system and vascular endothelium during angiogenesis. ..
Laue K, Daujat S, Crump J, Plaster N, Roehl H, Kimmel C, et al
. The multidomain protein Brpf1 binds histones and is required for Hox gene expression and segmental identity. Development. 2008;135:1935-46 pubmed publisher
..Here, based on genetic analyses in zebrafish, we identify the multidomain protein Brpf1 as a novel TrxG member with a central role during development...
B hne A, Darras A, D Cotta H, Baroiller J, Galiana Arnoux D, Volff J. The vertebrate makorin ubiquitin ligase gene family has been shaped by large-scale duplication and retroposition from an ancestral gonad-specific, maternal-effect gene. BMC Genomics. 2010;11:721 pubmed publisher
..Comparative expression analysis strongly suggests that the ancestral E3 ubiquitin ligase function of the single copy mkrn gene before duplication in vertebrates was gonad-specific, with maternal expression in early embryos...
Edmunds R, Su B, Balhoff J, Eames B, Dahdul W, Lapp H, et al
. Phenoscape: Identifying Candidate Genes for Evolutionary Phenotypes. Mol Biol Evol. 2016;33:13-24 pubmed publisher
..with the hypotheses that these features evolved through disruption in developmental pathways at, or upstream of, brpf1 and eda/edar for the ancestral losses of basihyal element and scales, respectively...