Gene Symbol: atp1a3b
Description: ATPase Na+/K+ transporting subunit alpha 3b
Alias: atp[a]3A, cb706, fj35g11, wu:fj35g11, wu:fq14g09, sodium/potassium-transporting ATPase subunit alpha-3, ATPase, Na+/K+ transporting, alpha 3b polypeptide
Carney S, Chen J, Burns C, Xiong K, Peterson R, Heideman W. Aryl hydrocarbon receptor activation produces heart-specific transcriptional and toxic responses in developing zebrafish. Mol Pharmacol. 2006;70:549-61 pubmed
..More than 70% of the transcripts in this heart-specific cluster promote cellular growth and proliferation. Thus, the developing heart stands out as being responsive to TCDD at both the level of toxicity and gene expression. ..
Liao B, Chen R, Hwang P. Expression regulation of Na+-K+-ATPase alpha1-subunit subtypes in zebrafish gill ionocytes. Am J Physiol Regul Integr Comp Physiol. 2009;296:R1897-906 pubmed publisher
..Taken together, zATP1a1a.1, zATP1a1a.2, and zATP1a1a.5 may provide driving force for Na+-coupled cotransporter activity specifically in NaR, NCC, and HR cells, respectively. ..
Duan J, Yu Y, Li Y, Li Y, Liu H, Jing L, et al
. Low-dose exposure of silica nanoparticles induces cardiac dysfunction via neutrophil-mediated inflammation and cardiac contraction in zebrafish embryos. Nanotoxicology. 2016;10:575-85 pubmed publisher
..muscle contraction via the down-regulated of related genes, such as ATPase-related genes (atp2a1l, atp1b2b, atp1a3b), calcium channel-related genes (cacna1ab, cacna1da) and the regulatory gene tnnc1a for cardiac troponin C...
Serluca F, Sidow A, Mably J, Fishman M. Partitioning of tissue expression accompanies multiple duplications of the Na+/K+ ATPase alpha subunit gene. Genome Res. 2001;11:1625-31 pubmed
..The duplications are accompanied by acquisition of clear functional specialization, consistent with the DDC model of genome evolution. ..
Stengel R, Rivera Milla E, Sahoo N, Ebert C, Bollig F, Heinemann S, et al
. Kcnh1 voltage-gated potassium channels are essential for early zebrafish development. J Biol Chem. 2012;287:35565-75 pubmed publisher
..These results reveal an unanticipated basic activity of kcnh1 that is crucial for early embryonic development and patterning. ..
Doğanlı C, Beck H, Ribera A, Oxvig C, Lykke Hartmann K. ?3Na+/K+-ATPase deficiency causes brain ventricle dilation and abrupt embryonic motility in zebrafish. J Biol Chem. 2013;288:8862-74 pubmed publisher
..In zebrafish, the transcripts of the two ATP1A3 orthologs, Atp1a3a and Atp1a3b, show distinct expression in the brain...
Liu H, Chu T, Chen L, Gui W, Zhu G. The cardiovascular toxicity of triadimefon in early life stage of zebrafish and potential implications to human health. Environ Pollut. 2017;231:1093-1103 pubmed publisher
..chain reaction) results demonstrated that the expression level of genes related to ATPase (atp2a1l, atp1b2b, atp1a3b), calcium channel (cacna1ab, cacna1da) and cardiac troponin C (tnnc1a) were significantly decreased after TF ..