Gene Symbol: ass1
Description: argininosuccinate synthase 1
Alias: ass, wu:fb95a04, wu:fc01e08, zgc:92051, argininosuccinate synthase, argininosuccinate synthetase 1, citrulline--aspartate ligase
Ding C, Zhang J, Zhao Y, Peng Z, Song D, Jiang J. Zebrafish as a potential model organism for drug test against hepatitis C virus. PLoS ONE. 2011;6:e22921 pubmed publisher
..Thus, zebrafish might be a model organism to host HCV, and this zebrafish/HCV (sub-replicon) system could be an animal model for anti-HCV drug screening and evaluation. ..
LeMoine C, Walsh P. Ontogeny of ornithine-urea cycle gene expression in zebrafish (Danio rerio). Am J Physiol Regul Integr Comp Physiol. 2013;304:R991-1000 pubmed publisher
..Overall, we conclude that the O-UC is functional in zebrafish embryos, providing further evidence that the capacity to produce urea via the O-UC is widespread in developing teleosts. ..
Zhao Y, Qin W, Zhang J, Hu Z, Tong J, Ding C, et al
. HCV IRES-mediated core expression in zebrafish. PLoS ONE. 2013;8:e56985 pubmed publisher
..These findings demonstrate the feasibility of the zebrafish model for screening of anti-HCV drugs targeting to HCV-IRES. The zebrafish system provides a novel evidence of using zebrafish as a HCV model organism. ..
Caldovic L, Haskins N, Mumo A, Majumdar H, Pinter M, Tuchman M, et al
. Expression pattern and biochemical properties of zebrafish N-acetylglutamate synthase. PLoS ONE. 2014;9:e85597 pubmed publisher
..N-acetylglutamate synthase (NAGS), carbamylphosphate synthetase III, ornithine transcarbamylase, argininosuccinate synthase, argininosuccinate lyase and arginase 1, and two membrane transporters, ornithine transporter and aralar,..
Gui J, Greene C, Sullivan C, Taylor W, Moore J, KIM C. Testing multiple hypotheses through IMP weighted FDR based on a genetic functional network with application to a new zebrafish transcriptome study. BioData Min. 2015;8:17 pubmed publisher
..We compared the mRNA expression for each group and found over 200 differentially expressed genes and several enriched pathways including defense response pathways, arsenic response pathways, and the Notch signaling pathway. ..