arr3a

Summary

Gene Symbol: arr3a
Description: arrestin 3a, retinal (X-arrestin)
Alias: arr3l, c-arrestin, zgc:92697, arrestin-C, arrestin 3, retinal (X-arrestin), like, cone arrestin
Species: zebrafish
Products:     arr3a

Top Publications

  1. Rinner O, Makhankov Y, Biehlmaier O, Neuhauss S. Knockdown of cone-specific kinase GRK7 in larval zebrafish leads to impaired cone response recovery and delayed dark adaptation. Neuron. 2005;47:231-42 pubmed
  2. Boubakri M, Chaya T, Hirata H, Kajimura N, Kuwahara R, Ueno A, et al. Loss of ift122, a Retrograde Intraflagellar Transport (IFT) Complex Component, Leads to Slow, Progressive Photoreceptor Degeneration Due to Inefficient Opsin Transport. J Biol Chem. 2016;291:24465-24474 pubmed
  3. Chen X, Sheng X, Zhuang W, Sun X, Liu G, Shi X, et al. GUCA1A mutation causes maculopathy in a five-generation family with a wide spectrum of severity. Genet Med. 2017;19:945-954 pubmed publisher
    ..The diverse pathogenic modes of GUCA1A mutations may explain the phenotypic diversities.Genet Med advance online publication 26 January 2017. ..
  4. Ile K, Kassen S, Cao C, Vihtehlic T, Shah S, Mousley C, et al. Zebrafish class 1 phosphatidylinositol transfer proteins: PITPbeta and double cone cell outer segment integrity in retina. Traffic. 2010;11:1151-67 pubmed publisher
    ..This study reports the initial description of the zebrafish class 1 mPITP family, and the first analysis of PITPbeta function in a vertebrate. ..
  5. Rey S, Boltaña S, Vargas R, Roher N, MacKenzie S. Combining animal personalities with transcriptomics resolves individual variation within a wild-type zebrafish population and identifies underpinning molecular differences in brain function. Mol Ecol. 2013;22:6100-15 pubmed publisher
    ..These differences can be mapped to distinct regions of the brain and provide a foundation towards understanding the coordination of underpinning adaptive molecular events within populations. ..
  6. Wu S, de Borsetti N, Bain E, Bulow C, Gamse J. Mediator subunit 12 coordinates intrinsic and extrinsic control of epithalamic development. Dev Biol. 2014;385:13-22 pubmed publisher
    ..We propose that the Mediator complex is responsible for subtle but significant changes in transcriptional timing and amplitude that are essential for coordinating the development of neurons in the epithalamus. ..
  7. Houbrechts A, Vergauwen L, Bagci E, Van Houcke J, Heijlen M, Kulemeka B, et al. Deiodinase knockdown affects zebrafish eye development at the level of gene expression, morphology and function. Mol Cell Endocrinol. 2016;424:81-93 pubmed publisher
    ..These data demonstrate the importance of TH-activating and -inactivating Ds for correct zebrafish eye development, and point to D3b as a central player. ..
  8. Alvarez C. On the origins of arrestin and rhodopsin. BMC Evol Biol. 2008;8:222 pubmed publisher
    ..Our arrestin findings have implications on the evolution of GPCR signaling, and on the biological roles of human alpha arrestins. ..
  9. Renninger S, Gesemann M, Neuhauss S. Cone arrestin confers cone vision of high temporal resolution in zebrafish larvae. Eur J Neurosci. 2011;33:658-67 pubmed publisher
    ..Comparison to opsin phosphorylation-deficient animals confirmed the role of cone arrestin in late cone response recovery...

More Information

Publications12

  1. Priyadarshini M, Tuimala J, Chen Y, Panula P. A zebrafish model of PINK1 deficiency reveals key pathway dysfunction including HIF signaling. Neurobiol Dis. 2013;54:127-38 pubmed publisher
    ..Our findings suggest that a lack of pink1 in zebrafish alters many vital and critical pathways in addition to the HIF signaling pathway. ..
  2. Nagashima M, Barthel L, Raymond P. A self-renewing division of zebrafish Müller glial cells generates neuronal progenitors that require N-cadherin to regenerate retinal neurons. Development. 2013;140:4510-21 pubmed publisher
    ..Genetic suppression of N-cadherin function interferes with basal migration of retinal progenitors and subsequent regeneration of HuC/D(+) inner retinal neurons. ..
  3. Huang L, Zuo Z, Zhang Y, Wu M, Lin J, Wang C. Use of toxicogenomics to predict the potential toxic effect of Benzo(a)pyrene on zebrafish embryos: ocular developmental toxicity. Chemosphere. 2014;108:55-61 pubmed publisher
    ..Our results were helpful for an understanding of the toxicity of BaP. This study also indicated that microarray analysis was effective for predicting the potential toxicity of chemicals with high sensitivity and accuracy. ..