Gene Symbol: arg2
Description: arginase 2
Alias: wu:fb67g02, zgc:65793, zgc:85630, arginase-2, mitochondrial, arginase, type II
Hu M, Gong H, Lin G, Hu S, Chen M, Huang S, et al
. XBP-1, a key regulator of unfolded protein response, activates transcription of IGF1 and Akt phosphorylation in zebrafish embryonic cell line. Biochem Biophys Res Commun. 2007;359:778-83 pubmed
SchÃ¼ttler A, Reiche K, Altenburger R, Busch W. The Transcriptome of the Zebrafish Embryo After Chemical Exposure: A Meta-Analysis. Toxicol Sci. 2017;157:291-304 pubmed publisher
..In future, improved time- and concentration-resolved experiments should offer better understanding of stress response patterns and access to mechanistic information. ..
Rawls J, Samuel B, Gordon J. Gnotobiotic zebrafish reveal evolutionarily conserved responses to the gut microbiota. Proc Natl Acad Sci U S A. 2004;101:4596-601 pubmed
..Together, these studies establish gnotobiotic zebrafish as a useful model for dissecting the molecular foundations of host-microbial interactions in the vertebrate digestive tract. ..
Hsiao C, You M, Guh Y, Ma M, Jiang Y, Hwang P. A positive regulatory loop between foxi3a and foxi3b is essential for specification and differentiation of zebrafish epidermal ionocytes. PLoS ONE. 2007;2:e302 pubmed
Dubrulle J, Jordan B, Akhmetova L, Farrell J, Kim S, Solnica Krezel L, et al
. Response to Nodal morphogen gradient is determined by the kinetics of target gene induction. elife. 2015;4: pubmed publisher
..Thus, the timing and magnitude of target gene expression can be used to modulate the range of expression and diversify the response to morphogen gradients. ..
Kopp R, Schwerte T, Egg M, Sandbichler A, Egger B, Pelster B. Chronic reduction in cardiac output induces hypoxic signaling in larval zebrafish even at a time when convective oxygen transport is not required. Physiol Genomics. 2010;42A:8-23 pubmed publisher
..The results showed that a chronic reduction in blood flow generated hypoxic molecular signals despite partial compensation by increased oxygen carrying capacity and transiently slowed the overall development of zebrafish bre larvae. ..
Huang Q, Huang H. Alterations of protein profile in zebrafish liver cells exposed to methyl parathion: a membrane proteomics approach. Chemosphere. 2012;87:68-76 pubmed publisher
..These data could provide useful insights for better understanding the hepatotoxic mechanisms of MP and develop novel protein biomarkers for effectively monitoring MP contamination level in aquatic environment. ..
Goodale B, La Du J, Tilton S, Sullivan C, Bisson W, Waters K, et al
. Ligand-Specific Transcriptional Mechanisms Underlie Aryl Hydrocarbon Receptor-Mediated Developmental Toxicity of Oxygenated PAHs. Toxicol Sci. 2015;147:397-411 pubmed publisher
..Identifying ligand-dependent AHR interactions and signaling pathways is essential for understanding toxicity of this class of environmentally relevant compounds. ..
Chen Q, Li C, Gong Z, Chan E, Snyder S, Lam S. Common deregulated gene expression profiles and morphological changes in developing zebrafish larvae exposed to environmental-relevant high to low concentrations of glucocorticoids. Chemosphere. 2017;172:429-439 pubmed publisher
..The common deregulated genes with the associated biological processes and morphological changes can be used for biological inference of glucocorticoid exposure in fish for future studies. ..