Gene Symbol: aqp3a
Description: aquaporin 3a
Alias: aqp3, wu:fa95h06, wu:fi13e05, zgc:55525, aquaporin 3a, aquaporin 3
Species: zebrafish
Products:     aqp3a

Top Publications

  1. Hamdi M, Sanchez M, Beene L, Liu Q, Landfear S, Rosen B, et al. Arsenic transport by zebrafish aquaglyceroporins. BMC Mol Biol. 2009;10:104 pubmed publisher
    ..Here, five genes which are close homologues to human AQP3, AQP9 and AQP10 were cloned from a zebrafish cDNA preparation...
  2. Tingaud Sequeira A, Calusinska M, Finn R, Chauvigné F, Lozano J, Cerdà J. The zebrafish genome encodes the largest vertebrate repertoire of functional aquaporins with dual paralogy and substrate specificities similar to mammals. BMC Evol Biol. 2010;10:38 pubmed publisher
    ..e., aquaporins (AQP0, -1 and -4), water and glycerol transporters or aquaglyceroporins (Glps; AQP3 and AQP7-10), a water and urea transporter (AQP8), and two unorthodox aquaporins (AQP11 and -12)...
  3. Horng J, Chao P, Chen P, Shih T, Lin L. Aquaporin 1 Is Involved in Acid Secretion by Ionocytes of Zebrafish Embryos through Facilitating CO2 Transport. PLoS ONE. 2015;10:e0136440 pubmed publisher
    ..In addition, exposure to an AQP inhibitor (PCMB) for 10 min also suppressed CO2-induced H+ secretion. Results from this study support our hypothesis and provide in vivo evidence of the physiological role of AQP1 in CO2 transport. ..
  4. Dong C, Chen L, Feng J, Xu J, Mahboob S, Al Ghanim K, et al. Genome Wide Identification, Phylogeny, and Expression of Aquaporin Genes in Common Carp (Cyprinus carpio). PLoS ONE. 2016;11:e0166160 pubmed publisher
    ..Moreover, the whole set of common carp aqp gene family provides an essential genomic resource for future biochemical, toxicological, physiological, and evolutionary studies in common carp. ..
  5. Chauvigné F, Lubzens E, Cerdà J. Design and characterization of genetically engineered zebrafish aquaporin-3 mutants highly permeable to the cryoprotectant ethylene glycol. BMC Biotechnol. 2011;11:34 pubmed publisher
    ..Artificial expression of water-selective aquaporins or aquaglyceroporins (GLPs), such as mammalian aquaporin-3 (AQP3), enhances cell permeability to water and cryoprotectants, but it is known that AQP3-mediated water and solute ..
  6. Hu B, Chen H, Liu X, Zhang C, Cole G, Lee J, et al. Transgenic overexpression of cdx1b induces metaplastic changes of gene expression in zebrafish esophageal squamous epithelium. Zebrafish. 2013;10:218-27 pubmed publisher
    ..However, cdx1b failed to induce histological IM, or to modulate cell proliferation and apoptosis in the squamous epithelium of adult transgenic zebrafish. ..
  7. Morató R, Chauvigné F, Novo S, Bonet S, Cerdà J. Enhanced water and cryoprotectant permeability of porcine oocytes after artificial expression of human and zebrafish aquaporin-3 channels. Mol Reprod Dev. 2014;81:450-61 pubmed publisher
    ..water and cryoprotectant permeability, which has been related to the transcriptional activation of aquaporin-3 (AQP3) channels at this stage of development...
  8. Sugano Y, Lindenmeyer M, Auberger I, Ziegler U, Segerer S, Cohen C, et al. The Rho-GTPase binding protein IQGAP2 is required for the glomerular filtration barrier. Kidney Int. 2015;88:1047-56 pubmed publisher
    ..Thus, IQGAP2 is a Rho-GTPase binding protein, highly abundant in human and zebrafish podocytes, which controls normal podocyte structure and function as evidenced in the zebrafish pronephros. ..
  9. Eskova A, Chauvigné F, Maischein H, Ammelburg M, Cerdà J, NUSSLEIN VOLHARD C, et al. Gain-of-function mutations in Aqp3a influence zebrafish pigment pattern formation through the tissue environment. Development. 2017;144:2059-2069 pubmed publisher
    ..Here, we describe novel zebrafish mau mutants, which encompass several dominant missense mutations in Aquaporin 3a (Aqp3a) that lead to broken stripes and short fins...