Gene Symbol: aoc1
Description: amine oxidase, copper containing 1
Alias: abp1, si:ch211-286c5.2, zgc:154101, amiloride-sensitive amine oxidase [copper-containing], amiloride binding protein 1 (amine oxidase (copper-containing)), dao, diamine oxidase, histaminase
Amo R, Aizawa H, Takahoko M, Kobayashi M, Takahashi R, Aoki T, et al
. Identification of the zebrafish ventral habenula as a homolog of the mammalian lateral habenula. J Neurosci. 2010;30:1566-74 pubmed publisher
..These findings indicated that the lateral habenular pathways are evolutionarily conserved pathways and might control adaptive behaviors in vertebrates through the regulation of monoaminergic activities...
Hong E, Santhakumar K, Akitake C, Ahn S, Thisse C, Thisse B, et al
. Cholinergic left-right asymmetry in the habenulo-interpeduncular pathway. Proc Natl Acad Sci U S A. 2013;110:21171-6 pubmed publisher
..Our studies of the newly identified cholinergic gene locus resolve the neurotransmitter identity of the zebrafish habenular nuclei and reveal functional asymmetry in a major cholinergic neuromodulatory pathway of the vertebrate brain. ..
Dean B, Erdoğan B, Gamse J, Wu S. Dbx1b defines the dorsal habenular progenitor domain in the zebrafish epithalamus. Neural Dev. 2014;9:20 pubmed publisher
..We provide clear evidence in support of dbx1b marking the progenitor populations that give rise to the dorsal habenulae. In addition, the expression of dbx1b in the dorsal diencephalon is tightly controlled by FGF signaling. ..
Amo R, Fredes F, Kinoshita M, Aoki R, Aizawa H, Agetsuma M, et al
. The habenulo-raphe serotonergic circuit encodes an aversive expectation value essential for adaptive active avoidance of danger. Neuron. 2014;84:1034-48 pubmed publisher
..Thus, vHb-MR circuit is essential for representing the level of expected danger and behavioral programming to adaptively avoid potential hazard. ..
deCarvalho T, Subedi A, Rock J, Harfe B, Thisse C, Thisse B, et al
. Neurotransmitter map of the asymmetric dorsal habenular nuclei of zebrafish. Genesis. 2014;52:636-55 pubmed publisher
..Although many aspects of habenular organization appear conserved with rodents, the zebrafish habenulae also possess unique properties that may underlie lateralization of their functions. ..