Gene Symbol: anxa4
Description: annexin A4
Alias: ANXIV, anx4, annexin A4, annexin 4
Lu A, Hu X, Xue J, Zhu J, Wang Y, Zhou G. Gene expression profiling in the skin of zebrafish infected with Citrobacter freundii. Fish Shellfish Immunol. 2012;32:273-83 pubmed publisher
..This is first report that skin play important roles in innate immune responses to bacterial infection, which contribute to understanding the defense mechanisms of the skin in fish. ..
Saxena S, Purushothaman S, Meghah V, Bhatti B, Poruri A, Meena Lakshmi M, et al
. Role of annexin gene and its regulation during zebrafish caudal fin regeneration. Wound Repair Regen. 2016;24:551-9 pubmed publisher
Farber S, De Rose R, Olson E, Halpern M. The zebrafish annexin gene family. Genome Res. 2003;13:1082-96 pubmed
..The differences in gene expression of recently duplicated anx genes could explain why highly related paralogs were maintained in the genome and did not rapidly become pseudogenes. ..
Wardle F, Odom D, Bell G, Yuan B, Danford T, Wiellette E, et al
. Zebrafish promoter microarrays identify actively transcribed embryonic genes. Genome Biol. 2006;7:R71 pubmed
..This approach will allow investigators to determine the genomic binding locations of DNA interacting proteins during development and expedite the assembly of the genetic networks that regulate embryogenesis. ..
Yee N, Zhou W, Liang I. Transient receptor potential ion channel Trpm7 regulates exocrine pancreatic epithelial proliferation by Mg2+-sensitive Socs3a signaling in development and cancer. Dis Model Mech. 2011;4:240-54 pubmed publisher
..Results of this study indicate that Trpm7 regulates exocrine pancreatic development via the Mg(2+)-sensitive Socs3a pathway, and suggest that aberrant TRPM7-mediated signaling contributes to pancreatic carcinogenesis. ..
Zhang D, Golubkov V, Han W, Correa R, Zhou Y, Lee S, et al
. Identification of Annexin A4 as a hepatopancreas factor involved in liver cell survival. Dev Biol. 2014;395:96-110 pubmed publisher
..Utilizing mass spectrometry and in vivo assays, we determined the molecular target of 2F11 to be Annexin A4 (Anxa4), a calcium binding protein...
Mosimann C, PanÃ¡kovÃ¡ D, Werdich A, Musso G, Burger A, Lawson K, et al
. Chamber identity programs drive early functional partitioning of the heart. Nat Commun. 2015;6:8146 pubmed publisher
..Our data establish that the transcriptional program driving cardiac septation regulates physiologic ventricle partitioning, which successively provides mechanical advantages of sequential contraction. ..