Gene Symbol: ankrd6b
Description: ankyrin repeat domain 6b
Alias: ankrd6, diversin, si:dkey-181i3none, ankyrin repeat domain-containing protein 6, ankyrin repeat domain 6
Katoh M, Katoh M. Identification and characterization of rat Ankrd6 gene in silico. Int J Mol Med. 2005;15:359-63 pubmed
..Human ANKRN6 is a Dgo homolog. Here, we identified and characterized rat Ankrd6 gene by using bioinformatics. Ankrd6 gene, consisting of 15 exons, was located within AC105547...
Schwarz Romond T, Asbrand C, Bakkers J, Kuhl M, Schaeffer H, Huelsken J, et al
. The ankyrin repeat protein Diversin recruits Casein kinase Iepsilon to the beta-catenin degradation complex and acts in both canonical Wnt and Wnt/JNK signaling. Genes Dev. 2002;16:2073-84 pubmed
..We describe here the vertebrate protein Diversin that interacts with two components of the canonical Wnt pathway, Casein kinase Iepsilon (CKIepsilon) and Axin/..
Brembeck F, Schwarz Romond T, Bakkers J, Wilhelm S, Hammerschmidt M, Birchmeier W. Essential role of BCL9-2 in the switch between beta-catenin's adhesive and transcriptional functions. Genes Dev. 2004;18:2225-30 pubmed
..During zebrafish embryogenesis, BCL9-2 acts in the Wnt8-signaling pathway and regulates mesoderm patterning. ..
Gonzaga Jauregui C, Harel T, Gambin T, Kousi M, Griffin L, Francescatto L, et al
. Exome Sequence Analysis Suggests that Genetic Burden Contributes to Phenotypic Variability and Complex Neuropathy. Cell Rep. 2015;12:1169-83 pubmed publisher
..Our findings suggest that the combinatorial effect of rare variants contributes to disease burden and variable expressivity. ..
Moeller H, Jenny A, Schaeffer H, Schwarz Romond T, Mlodzik M, Hammerschmidt M, et al
. Diversin regulates heart formation and gastrulation movements in development. Proc Natl Acad Sci U S A. 2006;103:15900-5 pubmed
..In this work we show that vertebrate Diversin, a potential orthologue of Drosophila Diego, controls fusion of heart precursors and gastrulation movements in ..
Cui S, Capecci L, Matthews R. Disruption of planar cell polarity activity leads to developmental biliary defects. Dev Biol. 2011;351:229-41 pubmed publisher
..Our results demonstrate that PCP plays an important role in vertebrate biliary development, interacting with other factors known to be involved in biliary morphogenesis. ..
Gordon L, Gribble K, Syrett C, Granato M. Initiation of synapse formation by Wnt-induced MuSK endocytosis. Development. 2012;139:1023-33 pubmed publisher
..Collectively, these findings suggest a general mechanism by which Wnt signals shape synaptic connectivity through localized receptor endocytosis. ..