Gene Symbol: alpha3 I
Description: collagen, type I, alpha 1b
Alias: alpha3(I), col1a3, hm:zeh0348, wu:fa95h05, wu:fd02a10, wu:fj59a10, collagen, type I, alpha 1b, collagen, type I, alpha 3, fj59a10
Morvan Dubois G, Le Guellec D, Garrone R, Zylberberg L, Bonnaud L. Phylogenetic analysis of vertebrate fibrillar collagen locates the position of zebrafish alpha3(I) and suggests an evolutionary link between collagen alpha chains and hox clusters. J Mol Evol. 2003;57:501-14 pubmed
..An evolutionary scenario is proposed in which phylogenetic relationships of the alpha chains of fibrillar collagens of vertebrates could be related to Hox cluster history. ..
Carlson P, Smalley D, Van Beneden R. Proteomic analysis of arsenic-exposed zebrafish (Danio rerio) identifies altered expression in proteins involved in fibrosis and lipid uptake in a gender-specific manner. Toxicol Sci. 2013;134:83-91 pubmed publisher
..The changes presented here seem to be most prevalent in lipid transport and metabolic pathways, suggesting a potential increase in fibrosis in males and decreased lipid accumulation and uptake in females. ..
Rodius S, Nazarov P, Nepomuceno Chamorro I, Jeanty C, GonzÃ¡lez Rosa J, Ibberson M, et al
. Transcriptional response to cardiac injury in the zebrafish: systematic identification of genes with highly concordant activity across in vivo models. BMC Genomics. 2014;15:852 pubmed publisher
..We identified genes with potential critical roles in the response to cardiac damage in the zebrafish. Their transcriptional activities are reproducible in different in vivo models of cardiac injury. ..
Biava P, Canaider S, Facchin F, Bianconi E, Ljungberg L, Rotilio D, et al
. Stem Cell Differentiation Stage Factors from Zebrafish Embryo: A Novel Strategy to Modulate the Fate of Normal and Pathological Human (Stem) Cells. Curr Pharm Biotechnol. 2015;16:782-92 pubmed
..In addition we report the data not yet published about a first protein analysis of the SCDSFs and about their role in a pathological condition like neurodegeneration. ..
Duran I, Csukasi F, Taylor S, Krakow D, Becerra J, Bombarely A, et al
. Collagen duplicate genes of bone and cartilage participate during regeneration of zebrafish fin skeleton. Gene Expr Patterns. 2015;19:60-9 pubmed publisher
..We also confirmed the hybrid nature of the fin exoskeleton and provided a complete description of those fibrillar collagens expressed during the formation of the fin skeleton. ..
Wehner D, Tsarouchas T, Michael A, Haase C, Weidinger G, Reimer M, et al
. Wnt signaling controls pro-regenerative Collagen XII in functional spinal cord regeneration in zebrafish. Nat Commun. 2017;8:126 pubmed publisher
..Here, the authors show that Wnt/?-catenin signaling in fibroblast-like cells at a lesion activates axon re-growth via deposition of Collagen XII. ..
Henke K, Daane J, Hawkins M, Dooley C, Busch Nentwich E, Stemple D, et al
. Genetic Screen for Postembryonic Development in the Zebrafish (Danio rerio): Dominant Mutations Affecting Adult Form. Genetics. 2017;207:609-623 pubmed publisher
..Taken together, these results show that dominant screens are a feasible and productive means to identify mutations that can further our understanding of gene function during postembryonic development and in disease. ..
Dubois G, Haftek Z, Crozet C, Garrone R, Le Guellec D. Structure and spatio temporal expression of the full length DNA complementary to RNA coding for alpha2 type I collagen of zebrafish. Gene. 2002;294:55-65 pubmed
..alpha2 mRNA were also detected in other tissues such as the tail fin primordium and the notochord primordium suggesting a participation of type I collagen in a pathway for notochord and tail formation. ..
Albertson R, Yan Y, Titus T, Pisano E, Vacchi M, Yelick P, et al
. Molecular pedomorphism underlies craniofacial skeletal evolution in Antarctic notothenioid fishes. BMC Evol Biol. 2010;10:4 pubmed publisher
..Our data support the hypothesis that early shifts in the relative timing of craniofacial skeletal gene expression may have had a significant impact on the adaptive radiation of Antarctic notothenioids into pelagic habitats. ..