Gene Symbol: aifm1
Description: apoptosis-inducing factor, mitochondrion-associated 1
Alias: AIF, pdcd8, zgc:91994, apoptosis-inducing factor 1, mitochondrial, programmed cell death 8 (apoptosis-inducing factor)
Miller G, Labut E, Lebold K, Floeter A, Tanguay R, Traber M. Zebrafish (Danio rerio) fed vitamin E-deficient diets produce embryos with increased morphologic abnormalities and mortality. J Nutr Biochem. 2012;23:478-86 pubmed publisher
..05) at 120 h post-fertillization than embryos from parents fed E+ or lab diets. This study documents for the first time that vitamin E is essential for normal zebrafish embryonic development. ..
Luzio A, Monteiro S, Fontaínhas Fernandes A, Pinto Carnide O, Matos M, Coimbra A. Copper induced upregulation of apoptosis related genes in zebrafish (Danio rerio) gill. Aquat Toxicol. 2013;128-129:183-9 pubmed publisher
..to different apoptosis pathways was done selecting p53, caspase-8, caspase-9 and apoptosis inducing factor (AIF) genes...
Inohara N, Nunez G. Genes with homology to mammalian apoptosis regulators identified in zebrafish. Cell Death Differ. 2000;7:509-10 pubmed
MarÃn Juez R, Rovira M, Crespo D, van der Vaart M, Spaink H, Planas J. GLUT2-mediated glucose uptake and availability are required for embryonic brain development in zebrafish. J Cereb Blood Flow Metab. 2015;35:74-85 pubmed publisher
..These results indicate that glut2 has an essential role during brain development by facilitating the uptake and availability of glucose and support the involvement of glut2 in brain glucose sensing. ..
Zhang Q, Cheng J, Xin Q. Effects of tetracycline on developmental toxicity and molecular responses in zebrafish (Danio rerio) embryos. Ecotoxicology. 2015;24:707-19 pubmed publisher
..The overall results indicate that tetracycline can produce oxidative stress and induce apoptosis, which brings about significant developmental delay in zebrafish embryos. ..
Zhou Z, Sun L. Edwardsiella tarda-Induced Inhibition of Apoptosis: A Strategy for Intracellular Survival. Front Cell Infect Microbiol. 2016;6:76 pubmed publisher
..tarda prevents apoptosis in teleost as a strategy for intracellular survival, and that some putative apoptotic genes of teleost function in the apoptosis pathway probably in a manner similar to that in mammalian systems. ..
Zhou T, Dong Q, Shen Y, Wu W, Wu H, Luo X, et al
. PEG-b-PCL polymeric nano-micelle inhibits vascular angiogenesis by activating p53-dependent apoptosis in zebrafish. Int J Nanomedicine. 2016;11:6517-6531 pubmed
..This study indicates that polymeric PEG-b-PCL nano-micelle could pose potential hazards to cardiovascular development. ..
Felix L, Serafim C, Valentim A, Antunes L, Matos M, Coimbra A. Apoptosis-related genes induced in response to ketamine during early life stages of zebrafish. Toxicol Lett. 2017;279:1-8 pubmed publisher
..After the 50% epiboly stage exposure, the mRNA levels of casp9 were increased at 8 and 24 hpf while aifm1 was affected at 24 hpf. Both tp53 and pcna expressions were increased at 8 hpf...
Mercer S, Odelberg S, Simon H. A dynamic spatiotemporal extracellular matrix facilitates epicardial-mediated vertebrate heart regeneration. Dev Biol. 2013;382:457-69 pubmed publisher
..Thus, the engineering of nature-tested extracellular matrices may provide new strategic opportunities for the enhancement of regenerative responses in mammals...