Genomes and Genes
Gene Symbol: ahr1b
Description: aryl hydrocarbon receptor 1b
Alias: si:dkey-159d6.1, aryl hydrocarbon receptor
- Garner L, Brown D, Di Giulio R. Knockdown of AHR1A but not AHR1B exacerbates PAH and PCB-126 toxicity in zebrafish (Danio rerio) embryos. Aquat Toxicol. 2013;142-143:336-46 pubmed publisherVarious environmental contaminants are known agonists for the aryl hydrocarbon receptor (AHR), which is highly conserved across vertebrate species...
- Zhang Y, Wang C, Huang L, Chen R, Chen Y, Zuo Z. Low-level pyrene exposure causes cardiac toxicity in zebrafish (Danio rerio) embryos. Aquat Toxicol. 2012;114-115:119-24 pubmed publisher..Although PAHs toxic endpoints show strong correlation with the aryl hydrocarbon receptor (AhR), a ligand activated transcription factor, and is thought to be a potent inducer of cytochrome ..
- Fraccalvieri D, Soshilov A, Karchner S, Franks D, Pandini A, Bonati L, et al. Comparative analysis of homology models of the AH receptor ligand binding domain: verification of structure-function predictions by site-directed mutagenesis of a nonfunctional receptor. Biochemistry. 2013;52:714-25 pubmed publisherThe aryl hydrocarbon receptor (AHR) is a ligand-dependent transcription factor that mediates the biological and toxic effects of a wide variety of structurally diverse chemicals, including the toxic environmental contaminant 2,3,7,8-..
- Wincent E, Stegeman J, JÃ¶nsson M. Combination effects of AHR agonists and Wnt/Î²-catenin modulators in zebrafish embryos: Implications for physiological and toxicological AHR functions. Toxicol Appl Pharmacol. 2015;284:163-79 pubmed publisher..The aryl hydrocarbon receptor (AHR) is well-known to mediate developmental toxicity of persistent dioxin-like compounds (DLCs)...
- Goodale B, La Du J, Bisson W, Janszen D, Waters K, Tanguay R. AHR2 mutant reveals functional diversity of aryl hydrocarbon receptors in zebrafish. PLoS ONE. 2012;7:e29346 pubmed publisherThe aryl hydrocarbon receptor (AHR) is well known for mediating the toxic effects of TCDD and has been a subject of intense research for over 30 years...
- Zhang Q, Zhang Y, Du J, Zhao M. Environmentally relevant levels of ?-cyhalothrin, fenvalerate, and permethrin cause developmental toxicity and disrupt endocrine system in zebrafish (Danio rerio) embryo. Chemosphere. 2017;185:1173-1180 pubmed publisher..These findings suggest that these 3 SPs may cause developmental toxicity to zebrafish larvae by disrupting endocrine signaling at environmentally relevant concentrations. ..