add3a

Summary

Gene Symbol: add3a
Description: adducin 3 (gamma) a
Alias: add3, wu:fb38g03, wu:fc16e06, zgc:55560, zgc:55992, zgc:77226, gamma-adducin
Species: zebrafish

Top Publications

  1. Deacon D, Nevis K, Cashman T, Zhou Y, Zhao L, Washko D, et al. The miR-143-adducin3 pathway is essential for cardiac chamber morphogenesis. Development. 2010;137:1887-96 pubmed publisher
    ..zebrafish that microRNA-143 (miR-143) is required for chamber morphogenesis through direct repression of adducin3 (add3), which encodes an F-actin capping protein...
  2. Tang V, COFER Z, Cui S, Sapp V, Loomes K, Matthews R. Loss of a Candidate Biliary Atresia Susceptibility Gene, add3a, Causes Biliary Developmental Defects in Zebrafish. J Pediatr Gastroenterol Nutr. 2016;63:524-530 pubmed
    ..gene leads to biliary defects, we performed morpholino antisense oligonucleotide (MO) knockdown studies targeting add3a and xpnpep1 in zebrafish...
  3. Zhao X, Zhao L, Tian T, Zhang Y, Tong J, Zheng X, et al. Interruption of cenph causes mitotic failure and embryonic death, and its haploinsufficiency suppresses cancer in zebrafish. J Biol Chem. 2010;285:27924-34 pubmed publisher
    ..Taken together, our findings uncover an essential role of cenph in mitosis and embryonic development and its association with tumor development. ..
  4. Lorent K, Gong W, Koo K, Waisbourd Zinman O, Karjoo S, Zhao X, et al. Identification of a plant isoflavonoid that causes biliary atresia. Sci Transl Med. 2015;7:286ra67 pubmed publisher
    ..Together, these findings provide direct evidence that BA could be initiated by perinatal exposure to an environmental toxin. ..