ada

Summary

Gene Symbol: ada
Description: adenosine deaminase
Alias: zgc:92028, ada1, adenosine aminohydrolase
Species: zebrafish

Top Publications

  1. doi PTZ-induced seizures inhibit adenosine deamination in adult zebrafish brain membranes
    Anna Maria Siebel
    Laboratório de Neuroquímica e Psicofarmacologia, Departamento de Biologia Celular e Molecular, Programa de Pós Graduação em Biologia Celular e Molecular, Faculdade de Biociencias, Pontificia Universidade Catolica do Rio Grande do Sul, Avenida Ipiranga, 6681, 90619 900 Porto Alegre, RS, Brazil
    Brain Res Bull 86:385-9. 2011
  2. doi Antiepileptic drugs prevent changes in adenosine deamination during acute seizure episodes in adult zebrafish
    Anna Maria Siebel
    Laboratório de Neuroquímica e Psicofarmacologia, Departamento de Biologia Celular e Molecular, Programa de Pós Graduação em Biologia Celular e Molecular, Faculdade de Biociencias, Pontificia Universidade Catolica do Rio Grande do Sul, Avenida Ipiranga, 6681, 90619 900 Porto Alegre, RS, Brazil
    Pharmacol Biochem Behav 104:20-6. 2013
  3. ncbi Adenosine deaminase-related genes: molecular identification, tissue expression pattern and truncated alternative splice isoform in adult zebrafish (Danio rerio)
    Denis Broock Rosemberg
    Departamento de Bioquimica, Instituto de Ciencias Basicas da Saude, Universidade Federal do Rio Grande do Sul Rua Ramiro Barcelos 2600 Anexo, 90035 003, Porto Alegre, RS, Brazil
    Life Sci 81:1526-34. 2007
  4. doi Ribosomal protein S19 deficiency in zebrafish leads to developmental abnormalities and defective erythropoiesis through activation of p53 protein family
    Nadia Danilova
    Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, UCLA, USA
    Blood 112:5228-37. 2008
  5. doi Influence of mercury chloride on adenosine deaminase activity and gene expression in zebrafish (Danio rerio) brain
    Mario Roberto Senger
    Programa de Pós Graduação em Ciências Biológicas Bioquímica, Departamento de Bioquimica, Instituto de Ciencias Basicas da Saude, Universidade Federal do Rio Grande do Sul Rua Ramiro Barcelos 2600 Anexo, 90035 003, Porto Alegre, RS, Brazil
    Neurotoxicology 31:291-6. 2010
  6. doi Acute restraint stress in zebrafish: behavioral parameters and purinergic signaling
    Angelo L Piato
    Laboratório de Neuroquímica e Psicofarmacologia, Departamento de Biologia Celular e Molecular, Faculdade de Biociencias, Pontificia Universidade Catolica do Rio Grande do Sul, Avenida Ipiranga, 6681 Predio 12D, Sala 340, Porto Alegre, RS 90619 900, Brazil
    Neurochem Res 36:1876-86. 2011

Scientific Experts

  • Angelo L Piato
  • Anna Maria Siebel
  • Carla Denise Bonan
  • Mauricio Reis Bogo
  • Denis Broock Rosemberg
  • Kelly Juliana Seibt
  • Mario Roberto Senger
  • Renato Dutra Dias
  • Nadia Danilova
  • Isabel Costa Schaefer
  • Laura Roesler Nery
  • Katiucia Marques Capiotti
  • Kathleen M Sakamoto
  • Shuo Lin
  • Diogo Onofre Souza
  • Marcus Rodrigo Guidoti
  • Eduardo Pacheco Rico

Detail Information

Publications6

  1. doi PTZ-induced seizures inhibit adenosine deamination in adult zebrafish brain membranes
    Anna Maria Siebel
    Laboratório de Neuroquímica e Psicofarmacologia, Departamento de Biologia Celular e Molecular, Programa de Pós Graduação em Biologia Celular e Molecular, Faculdade de Biociencias, Pontificia Universidade Catolica do Rio Grande do Sul, Avenida Ipiranga, 6681, 90619 900 Porto Alegre, RS, Brazil
    Brain Res Bull 86:385-9. 2011
    ..The hydrolysis of ATP by ectonucleotidases is an important source of adenosine, and adenosine deaminase (ADA) contributes to the regulation of this nucleoside concentration through its deamination...
  2. doi Antiepileptic drugs prevent changes in adenosine deamination during acute seizure episodes in adult zebrafish
    Anna Maria Siebel
    Laboratório de Neuroquímica e Psicofarmacologia, Departamento de Biologia Celular e Molecular, Programa de Pós Graduação em Biologia Celular e Molecular, Faculdade de Biociencias, Pontificia Universidade Catolica do Rio Grande do Sul, Avenida Ipiranga, 6681, 90619 900 Porto Alegre, RS, Brazil
    Pharmacol Biochem Behav 104:20-6. 2013
    ..The modulation of extracellular adenosine levels by ectonucleotidase and adenosine deaminase (ADA) activities may represent a key mechanism in the control of epileptogenesis...
  3. ncbi Adenosine deaminase-related genes: molecular identification, tissue expression pattern and truncated alternative splice isoform in adult zebrafish (Danio rerio)
    Denis Broock Rosemberg
    Departamento de Bioquimica, Instituto de Ciencias Basicas da Saude, Universidade Federal do Rio Grande do Sul Rua Ramiro Barcelos 2600 Anexo, 90035 003, Porto Alegre, RS, Brazil
    Life Sci 81:1526-34. 2007
    ..Two members of ADA subfamilies, known as ADA1 and ADA2, were described and evidence demonstrated another similar protein group named ADAL (adenosine deaminase "..
  4. doi Ribosomal protein S19 deficiency in zebrafish leads to developmental abnormalities and defective erythropoiesis through activation of p53 protein family
    Nadia Danilova
    Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, UCLA, USA
    Blood 112:5228-37. 2008
    ..Ribosomal stress syndromes represent a broader spectrum of human congenital diseases caused by genotoxic stress; therefore, imbalance of p53 family members may become a new target for therapeutics...
  5. doi Influence of mercury chloride on adenosine deaminase activity and gene expression in zebrafish (Danio rerio) brain
    Mario Roberto Senger
    Programa de Pós Graduação em Ciências Biológicas Bioquímica, Departamento de Bioquimica, Instituto de Ciencias Basicas da Saude, Universidade Federal do Rio Grande do Sul Rua Ramiro Barcelos 2600 Anexo, 90035 003, Porto Alegre, RS, Brazil
    Neurotoxicology 31:291-6. 2010
    ..In this study we investigated the effects of mercury chloride on soluble and membrane adenosine deaminase (ADA) activity and gene expression in zebrafish brain...
  6. doi Acute restraint stress in zebrafish: behavioral parameters and purinergic signaling
    Angelo L Piato
    Laboratório de Neuroquímica e Psicofarmacologia, Departamento de Biologia Celular e Molecular, Faculdade de Biociencias, Pontificia Universidade Catolica do Rio Grande do Sul, Avenida Ipiranga, 6681 Predio 12D, Sala 340, Porto Alegre, RS 90619 900, Brazil
    Neurochem Res 36:1876-86. 2011
    ..ARS significantly increased ATP hydrolysis, decreased cytosolic ADA activity, and changed the entpd and adora gene expression...