Gene Symbol: ace
Description: angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
Alias: fb81h03, si:ch211-124e16.1, wu:fb81h03, angiotensin-converting enzyme
Species: zebrafish

Top Publications

  1. Slade L, Cowie A, Martyniuk C, Kienesberger P, Pulinilkunnil T. Dieldrin Augments mTOR Signaling and Regulates Genes Associated with Cardiovascular Disease in the Adult Zebrafish Heart (Danio rerio). J Pharmacol Exp Ther. 2017;361:375-385 pubmed publisher
    ..Our data demonstrate that dieldrin induces genes associated with cardiovascular dysfunction and compromised lysosomal physiology, thereby identifying a novel mechanism for pesticide-induced cardiotoxicity. ..
  2. Prokop J, Petri V, Shimoyama M, Watanabe I, Casarini D, Leeper T, et al. Structural libraries of protein models for multiple species to understand evolution of the renin-angiotensin system. Gen Comp Endocrinol. 2015;215:106-16 pubmed publisher
  3. Wang Y, Wang H, Li M, Gao Z, Zhang S. Identification, expression and regulation of amphioxus G6Pase gene with an emphasis on origin of liver. Gen Comp Endocrinol. 2015;214:9-16 pubmed publisher
    ..Collectively, all these provide functional evidences supporting the notion that the digestive diverticulum is the liver homologue playing a key role in maintaining the glucose homeostasis in amphioxus. ..
  4. Kitambi S, McCulloch K, Peterson R, Malicki J. Small molecule screen for compounds that affect vascular development in the zebrafish retina. Mech Dev. 2009;126:464-77 pubmed
    ..This work demonstrates the utility of zebrafish as a screening tool for small molecules that affect eye vasculature and presents several compounds of potential therapeutic importance. ..
  5. Wirbisky S, Weber G, Sepúlveda M, Lin T, Jannasch A, Freeman J. An embryonic atrazine exposure results in reproductive dysfunction in adult zebrafish and morphological alterations in their offspring. Sci Rep. 2016;6:21337 pubmed publisher
    ..This study provides evidence to support atrazine as an EDC causing reproductive dysfunction and molecular alterations in adults exposed only during embryogenesis and morphological alterations in their offspring. ..