YPT11

Summary

Gene Symbol: YPT11
Description: Ypt11p
Species:

Top Publications

  1. ncbi Saccharomyces cerevisiae Pra1p/Yip3p interacts with Yip1p and Rab proteins
    Monica Calero
    Department of Molecular Medicine, Cornell University, Ithaca, New York 14853 6401, USA
    Biochem Biophys Res Commun 290:676-81. 2002
  2. ncbi Subunit organization and Rab interactions of Vps-C protein complexes that control endolysosomal membrane traffic
    Rachael L Plemel
    Department of Biochemistry, University of Washington, Seattle, WA 98195 3750, USA
    Mol Biol Cell 22:1353-63. 2011
  3. ncbi PI4P and Rab inputs collaborate in myosin-V-dependent transport of secretory compartments in yeast
    Felipe H Santiago-Tirado
    Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA
    Dev Cell 20:47-59. 2011
  4. ncbi Ypt11 functions in bud-directed transport of the Golgi by linking Myo2 to the coatomer subunit Ret2
    Seisuke Arai
    Department of Biotechnology, University of Tokyo, Yayoi, Bunkyo ku, Tokyo 113 8657, Japan
    Curr Biol 18:987-91. 2008
  5. ncbi Bioinformatic and comparative localization of Rab proteins reveals functional insights into the uncharacterized GTPases Ypt10p and Ypt11p
    Stéphanie Buvelot Frei
    Institut fur Biochemie, Swiss Federal Institute of Technology ETH, CH 8093 Zurich, Switzerland
    Mol Cell Biol 26:7299-317. 2006
  6. ncbi Yeast Ypt11 is targeted to recycling endosomes in mammalian cells
    Mark Kail
    Department of Experimental Tumorbiology, University Muenster, Badestr 9, 48149 Muenster, Germany
    Biol Cell 97:651-8. 2005
  7. ncbi Genetic analysis of yeast Yip1p function reveals a requirement for Golgi-localized rab proteins and rab-Guanine nucleotide dissociation inhibitor
    Catherine Z Chen
    Department of Molecular Medicine, Cornell University, Ithaca, New York 14853 6401, USA
    Genetics 168:1827-41. 2004
  8. ncbi A type V myosin (Myo2p) and a Rab-like G-protein (Ypt11p) are required for retention of newly inherited mitochondria in yeast cells during cell division
    Istvan R Boldogh
    Department of Anatomy and Cell Biology, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Mol Biol Cell 15:3994-4002. 2004
  9. ncbi Mmr1p is a mitochondrial factor for Myo2p-dependent inheritance of mitochondria in the budding yeast
    Takashi Itoh
    Department of Biological Sciences, Graduate School of Science, University of Tokyo, Tokyo, Japan
    EMBO J 23:2520-30. 2004
  10. ncbi Complex formation with Ypt11p, a rab-type small GTPase, is essential to facilitate the function of Myo2p, a class V myosin, in mitochondrial distribution in Saccharomyces cerevisiae
    Takashi Itoh
    Department of Biological Sciences, Graduate School of Science, University of Tokyo, Hongo, Tokyo 113 0033, Japan
    Mol Cell Biol 22:7744-57. 2002

Scientific Experts

  • Monica Calero
  • Rachael L Plemel
  • Christopher L Brett
  • Ruth N Collins
  • Takashi Itoh
  • Catherine Z Chen
  • Johannes Förtsch
  • Felipe H Santiago-Tirado
  • Braden T Lobingier
  • Alexey J Merz
  • Seisuke Arai
  • Stéphanie Buvelot Frei
  • Mark Kail
  • Istvan R Boldogh
  • Akio Toh-E
  • Yasushi Matsui
  • Cortney G Angers
  • Melanie Krist
  • Daniel P Nickerson
  • Benedikt Westermann
  • Daniel Schott
  • Debra Sprague
  • Andrew Paulsel
  • Aster Legesse-Miller
  • Eric Hummel
  • Anthony Bretscher
  • Marissa Vignali
  • Yoichi Noda
  • Satoko Kainuma
  • Braden T Lobinger
  • Koji Yoda
  • Stanley Fields
  • Ikuo Wada
  • Gary R Whittaker
  • Stephanie Janeczko
  • Peter B Rahl
  • Maria Nussbaum
  • Andrew D Regan
  • Benjamin J Briggs
  • Yves Barral
  • David Vaux
  • Jens Boettcher
  • Mike Hollinshead
  • Angelika Barnekow
  • Miriam Kaufmann
  • Matthew Heidtman
  • Sharmilee L Ramcharan
  • Liza A Pon
  • Hyeong-Cheol Yang
  • Carol J DeRegis
  • Hyeong Cheol Yang
  • Charles Barlowe
  • Nena J Winand
  • Akiko Watabe

Detail Information

Publications13

  1. ncbi Saccharomyces cerevisiae Pra1p/Yip3p interacts with Yip1p and Rab proteins
    Monica Calero
    Department of Molecular Medicine, Cornell University, Ithaca, New York 14853 6401, USA
    Biochem Biophys Res Commun 290:676-81. 2002
    ..The interactions between Pra1p/Yip3p and Rab proteins are dependent on the presence of the Rab protein C-terminal cysteines and require C-terminal prenylation...
  2. ncbi Subunit organization and Rab interactions of Vps-C protein complexes that control endolysosomal membrane traffic
    Rachael L Plemel
    Department of Biochemistry, University of Washington, Seattle, WA 98195 3750, USA
    Mol Biol Cell 22:1353-63. 2011
    ..Biochemical and genetic experiments demonstrate the importance of these regions, revealing the Vps11 CTD as a key integrator of Vps-C complex assembly, Rab signaling, and endosomal and lysosomal traffic...
  3. ncbi PI4P and Rab inputs collaborate in myosin-V-dependent transport of secretory compartments in yeast
    Felipe H Santiago-Tirado
    Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA
    Dev Cell 20:47-59. 2011
    ..Thus, we show that a coincidence detection mechanism coordinates inputs from PI4P and the appropriate Rab for secretory compartment transport...
  4. ncbi Ypt11 functions in bud-directed transport of the Golgi by linking Myo2 to the coatomer subunit Ret2
    Seisuke Arai
    Department of Biotechnology, University of Tokyo, Yayoi, Bunkyo ku, Tokyo 113 8657, Japan
    Curr Biol 18:987-91. 2008
    ..However, the mechanism that links the Golgi to Myo2 is unknown. Here, we report that Ypt11, a Rab GTPase that reportedly interacts with Myo2, binds to Ret2, a subunit of the coatomer complex...
  5. ncbi Bioinformatic and comparative localization of Rab proteins reveals functional insights into the uncharacterized GTPases Ypt10p and Ypt11p
    Stéphanie Buvelot Frei
    Institut fur Biochemie, Swiss Federal Institute of Technology ETH, CH 8093 Zurich, Switzerland
    Mol Cell Biol 26:7299-317. 2006
    ....
  6. ncbi Yeast Ypt11 is targeted to recycling endosomes in mammalian cells
    Mark Kail
    Department of Experimental Tumorbiology, University Muenster, Badestr 9, 48149 Muenster, Germany
    Biol Cell 97:651-8. 2005
    BACKGROUND INFORMATION: In yeast, Ypt11 or Ypt32 along with the highly homologous Ypt8 or Ypt31 has been reported to be an essential component of intra-Golgi trafficking and has been implicated in the budding of vesicles from the most ..
  7. ncbi Genetic analysis of yeast Yip1p function reveals a requirement for Golgi-localized rab proteins and rab-Guanine nucleotide dissociation inhibitor
    Catherine Z Chen
    Department of Molecular Medicine, Cornell University, Ithaca, New York 14853 6401, USA
    Genetics 168:1827-41. 2004
    ....
  8. ncbi A type V myosin (Myo2p) and a Rab-like G-protein (Ypt11p) are required for retention of newly inherited mitochondria in yeast cells during cell division
    Istvan R Boldogh
    Department of Anatomy and Cell Biology, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Mol Biol Cell 15:3994-4002. 2004
    ..We found that deletion of YPT11, reduction of the length of the Myo2p lever arm (myo2-Delta6IQ), or deletion of MYO4 (the other yeast myosin V), ..
  9. ncbi Mmr1p is a mitochondrial factor for Myo2p-dependent inheritance of mitochondria in the budding yeast
    Takashi Itoh
    Department of Biological Sciences, Graduate School of Science, University of Tokyo, Tokyo, Japan
    EMBO J 23:2520-30. 2004
    ..Genetical analysis revealed that the Mmr1p-Myo2p pathway is independent of the Ypt11p-Myo2p pathway, suggesting that an essential system for mitochondrial distribution is composed of two independent Myo2p pathways...
  10. ncbi Complex formation with Ypt11p, a rab-type small GTPase, is essential to facilitate the function of Myo2p, a class V myosin, in mitochondrial distribution in Saccharomyces cerevisiae
    Takashi Itoh
    Department of Biological Sciences, Graduate School of Science, University of Tokyo, Hongo, Tokyo 113 0033, Japan
    Mol Cell Biol 22:7744-57. 2002
    ..Mutational analysis of YPT11 suggests that Myo2p is a putative effector of Ypt11p...
  11. ncbi Identification of the novel proteins Yip4p and Yip5p as Rab GTPase interacting factors
    Monica Calero
    Department of Molecular Medicine, Cornell University, Ithaca, NY 14853 6401, USA
    FEBS Lett 515:89-98. 2002
    ....
  12. ncbi The myosin-related motor protein Myo2 is an essential mediator of bud-directed mitochondrial movement in yeast
    Johannes Förtsch
    Institut fur Zellbiologie, Universitat Bayreuth, Germany
    J Cell Biol 194:473-88. 2011
    ..cargo binding domain impair entry of mitochondria into the bud and are synthetically lethal with deletion of the YPT11 gene encoding a rab-type guanosine triphosphatase...
  13. ncbi Efficient termination of vacuolar Rab GTPase signaling requires coordinated action by a GAP and a protein kinase
    Christopher L Brett
    Department of Biochemistry, University of Washington, Seattle, WA 98195, USA
    J Cell Biol 182:1141-51. 2008
    ..We propose that signal propagation through the Ypt7 pathway is controlled by integrated feedback and feed-forward loops. In this model, Yck3 enforces a requirement for the activated Rab in docking and fusion...