Genomes and Genes

Species

Gene Symbol: tp63

Description: tumor protein p63

Alias: Xp63, ket, np63, p63, tp73l, trp63, tumor protein 63

Species: western clawed frog

Fischer B, Metzger M, Richardson R, Knyphausen P, Ramezani T, Franzen R, et al. p53 and TAp63 promote keratinocyte proliferation and differentiation in breeding tubercles of the zebrafish. PLoS Genet. 2014;10:e1004048 pubmed publisher

p63 is a multi-isoform member of the p53 family of transcription factors. There is compelling genetic evidence that ?Np63 isoforms are needed for keratinocyte proliferation and stemness in the developing vertebrate epidermis...