neu3

Summary

Gene Symbol: neu3
Description: sialidase 3 (membrane sialidase)
Alias: sial3, sialidase-3, neuraminidase 3, sialidase NEU3.1
Species: western clawed frog

Top Publications

  1. Monti E, Bassi M, Papini N, Riboni M, Manzoni M, Venerando B, et al. Identification and expression of NEU3, a novel human sialidase associated to the plasma membrane. Biochem J. 2000;349:343-51 pubmed
    ..Here we describe the identification and expression of a human plasma-membrane-associated sialidase, NEU3, isolated starting from an expressed sequence tag (EST) clone...
  2. Monti E, Bassi M, Bresciani R, Civini S, Croci G, Papini N, et al. Molecular cloning and characterization of NEU4, the fourth member of the human sialidase gene family. Genomics. 2004;83:445-53 pubmed
    ..unique among mammalian sialidases, shows a high degree of homology for NEU2 and the plasma membrane-associated (NEU3) sialidases. RNA dot-blot analysis showed a low but wide expression pattern, with the highest level in liver...
  3. Giacopuzzi E, Barlati S, Preti A, Venerando B, Monti E, Borsani G, et al. Gallus gallus NEU3 sialidase as model to study protein evolution mechanism based on rapid evolving loops. BMC Biochem. 2011;12:45 pubmed publisher
    ..Gallus gallus (Gg) genome contains one NEU3 gene encoding a protein with a unique 188 amino acid sequence mainly constituted by a peptide motif repeated six ..
  4. Monti E, Preti A, Rossi E, Ballabio A, Borsani G. Cloning and characterization of NEU2, a human gene homologous to rodent soluble sialidases. Genomics. 1999;57:137-43 pubmed publisher
    ..Northern blot analysis revealed expression of the NEU2 transcript only in skeletal muscle...
  5. Giacopuzzi E, Bresciani R, Schauer R, Monti E, Borsani G. New insights on the sialidase protein family revealed by a phylogenetic analysis in metazoa. PLoS ONE. 2012;7:e44193 pubmed publisher
    ..sialidase forms are known in vertebrates: the lysosomal NEU1, the cytosolic NEU2 and the membrane-associated NEU3 and NEU4...