Gene Symbol: LOC100496083
Alias: sialidase-4, sialidase NEU3.2
Species: western clawed frog
Monti E, Bassi M, Papini N, Riboni M, Manzoni M, Venerando B, et al
. Identification and expression of NEU3, a novel human sialidase associated to the plasma membrane. Biochem J. 2000;349:343-51 pubmed
..8. Immunofluorescence staining of the transfected COS7 cells demonstrated the protein's localization in the plasma membrane. ..
Monti E, Bassi M, Bresciani R, Civini S, Croci G, Papini N, et al
. Molecular cloning and characterization of NEU4, the fourth member of the human sialidase gene family. Genomics. 2004;83:445-53 pubmed
..Immunofluorescence staining and Western blot analysis demonstrated the association of NEU4 with the inner cell membranes. ..
Giacopuzzi E, Barlati S, Preti A, Venerando B, Monti E, Borsani G, et al
. Gallus gallus NEU3 sialidase as model to study protein evolution mechanism based on rapid evolving loops. BMC Biochem. 2011;12:45 pubmed publisher
..Giving the peculiar organization of the loop region identified in Gg NEU3, this protein can be considered of particular interest in such evolutionary studies and to get deeper insights in sialidase evolution. ..
Monti E, Preti A, Rossi E, Ballabio A, Borsani G. Cloning and characterization of NEU2, a human gene homologous to rodent soluble sialidases. Genomics. 1999;57:137-43 pubmed publisher
..Northern blot analysis revealed expression of the NEU2 transcript only in skeletal muscle...
Giacopuzzi E, Bresciani R, Schauer R, Monti E, Borsani G. New insights on the sialidase protein family revealed by a phylogenetic analysis in metazoa. PLoS ONE. 2012;7:e44193 pubmed publisher
..Moreover, we further confirm findings on the catalytic residues and identified enzyme loop portions that behave as rapidly diverging regions and may be involved in the evolution of specific properties of sialidases...