Genomes and Genes
Gene Symbol: VVA1465
Description: Zinc metalloprotease, vibriolysin
Species: Vibrio vulnificus YJ016
- Cloning and nucleotide sequencing of the protease gene of Vibrio vulnificusJ C Cheng
Department of Microbiology and Immunology, College of Medicine, National Cheng Kung University, Tainan, Taiwan, ROC
Gene 183:255-7. 1996..The transcription start point was also determined by primer extension. The product of this gene is very likely the secretory neutral metalloprotease that has been purified and characterized previously...
- Cloning and characterization of the gene (empV) encoding extracellular metalloprotease from Vibrio vulnificusY C Chuang
Department of Internal Medicine, National Cheng Kung University Hospital, Tainan, Taiwan
Gene 189:163-8. 1997..anguillarum metalloprotease (EmpA), V. cholerae HA/protease (HprC), and V proteolyticus neutral protease (NprP), particularly with respect to active-site residues, zinc-binding residues, and cysteine residues...
- Construction and phenotypic evaluation of a Vibrio vulnificus vvpE mutant for elastolytic proteaseK C Jeong
Department of Food Science and Technology, Institute of Biotechnology, Chonnam National University, Kwang Ju, 500 757, South Korea
Infect Immun 68:5096-106. 2000..However, V. vulnificus utilizes a variety of virulence factors; hence, the effects of inactivation of elastase alone could be masked by other compensatory virulence factors...
- High growing ability of Vibrio vulnificus biotype 1 is essential for production of a toxic metalloprotease causing systemic diseases in humansHirofumi Watanabe
Faculty of Pharmaceutical Sciences, Okayama University, Tsushima Naka, 700 8530, Okayama, Japan
Microb Pathog 36:117-23. 2004..This prominent ability of biotype 1 in growth and protease production may contribute to cause serious systemic diseases in humans...