VVA1465

Summary

Gene Symbol: VVA1465
Description: Zinc metalloprotease, vibriolysin
Species: Vibrio vulnificus YJ016

Top Publications

  1. pmc Crystallization of an atypical short-chain dehydrogenase from Vibrio vulnificus lacking the conserved catalytic tetrad
    GĂ©raldine Buysschaert
    Unit for Structural Biology, Laboratory for Protein Biochemistry and Biomolecular Engineering, Unit for Structural Biology, Ghent University, K L Ledeganckstraat 35, B 9000 Ghent, Belgium
    Acta Crystallogr Sect F Struct Biol Cryst Commun 68:771-4. 2012
  2. ncbi Cloning and nucleotide sequencing of the protease gene of Vibrio vulnificus
    J C Cheng
    Department of Microbiology and Immunology, College of Medicine, National Cheng Kung University, Tainan, Taiwan, ROC
    Gene 183:255-7. 1996
  3. ncbi Cloning and characterization of the gene (empV) encoding extracellular metalloprotease from Vibrio vulnificus
    Y C Chuang
    Department of Internal Medicine, National Cheng Kung University Hospital, Tainan, Taiwan
    Gene 189:163-8. 1997
  4. pmc Construction and phenotypic evaluation of a Vibrio vulnificus vvpE mutant for elastolytic protease
    K C Jeong
    Department of Food Science and Technology, Institute of Biotechnology, Chonnam National University, Kwang Ju, 500 757, South Korea
    Infect Immun 68:5096-106. 2000
  5. ncbi High growing ability of Vibrio vulnificus biotype 1 is essential for production of a toxic metalloprotease causing systemic diseases in humans
    Hirofumi Watanabe
    Faculty of Pharmaceutical Sciences, Okayama University, Tsushima Naka, 700 8530, Okayama, Japan
    Microb Pathog 36:117-23. 2004

Detail Information

Publications5

  1. pmc Crystallization of an atypical short-chain dehydrogenase from Vibrio vulnificus lacking the conserved catalytic tetrad
    GĂ©raldine Buysschaert
    Unit for Structural Biology, Laboratory for Protein Biochemistry and Biomolecular Engineering, Unit for Structural Biology, Ghent University, K L Ledeganckstraat 35, B 9000 Ghent, Belgium
    Acta Crystallogr Sect F Struct Biol Cryst Commun 68:771-4. 2012
    ..This work sets the stage for deriving the identity of the natural substrate of SDRvv and the structure-function landscape of typical and atypical SDRs...
  2. ncbi Cloning and nucleotide sequencing of the protease gene of Vibrio vulnificus
    J C Cheng
    Department of Microbiology and Immunology, College of Medicine, National Cheng Kung University, Tainan, Taiwan, ROC
    Gene 183:255-7. 1996
    ..The transcription start point was also determined by primer extension. The product of this gene is very likely the secretory neutral metalloprotease that has been purified and characterized previously...
  3. ncbi Cloning and characterization of the gene (empV) encoding extracellular metalloprotease from Vibrio vulnificus
    Y C Chuang
    Department of Internal Medicine, National Cheng Kung University Hospital, Tainan, Taiwan
    Gene 189:163-8. 1997
    ..anguillarum metalloprotease (EmpA), V. cholerae HA/protease (HprC), and V proteolyticus neutral protease (NprP), particularly with respect to active-site residues, zinc-binding residues, and cysteine residues...
  4. pmc Construction and phenotypic evaluation of a Vibrio vulnificus vvpE mutant for elastolytic protease
    K C Jeong
    Department of Food Science and Technology, Institute of Biotechnology, Chonnam National University, Kwang Ju, 500 757, South Korea
    Infect Immun 68:5096-106. 2000
    ..However, V. vulnificus utilizes a variety of virulence factors; hence, the effects of inactivation of elastase alone could be masked by other compensatory virulence factors...
  5. ncbi High growing ability of Vibrio vulnificus biotype 1 is essential for production of a toxic metalloprotease causing systemic diseases in humans
    Hirofumi Watanabe
    Faculty of Pharmaceutical Sciences, Okayama University, Tsushima Naka, 700 8530, Okayama, Japan
    Microb Pathog 36:117-23. 2004
    ..This prominent ability of biotype 1 in growth and protease production may contribute to cause serious systemic diseases in humans...