Gene Symbol: B13R
Description: temporal expression: early
Alias: SPI-2/CrmA inhibits Fas-mediated apoptosis, IL-1 convertase, lipoxygenase pathway
Species: Vaccinia virus
Products:     B13R

Top Publications

  1. Smith G, Howard S, Chan Y. Vaccinia virus encodes a family of genes with homology to serine proteinase inhibitors. J Gen Virol. 1989;70 ( Pt 9):2333-43 pubmed publisher
    ..One of the vaccinia virus serpins identified here (B13R) shares 92% amino acid identity with the serpin from cowpox virus and 46% and 19% identity with vaccinia serpins ..
  2. Kotwal G, Moss B. Vaccinia virus encodes two proteins that are structurally related to members of the plasma serine protease inhibitor superfamily. J Virol. 1989;63:600-6 pubmed
    ..Evidence for a cowpox virus homolog of SPI-1 was obtained by DNA hybridization. Thus, the presence of two genes that belong to the plasma serine protease inhibitor superfamily may be characteristic of orthopoxviruses. ..