Gene Symbol: A3L
Description: temporal expression: late
Alias: p4b precursor of core protein 4b
Species: Vaccinia virus
Products:     A3L

Top Publications

  1. Garcel A, Crance J, Drillien R, Garin D, Favier A. Genomic sequence of a clonal isolate of the vaccinia virus Lister strain employed for smallpox vaccination in France and its comparison to other orthopoxviruses. J Gen Virol. 2007;88:1906-16 pubmed
    ..These studies highlight the heterogeneity between VACV strains and provide a basis to better understand differences in safety and efficacy of smallpox vaccines. ..
  2. Qin L, Favis N, Famulski J, Evans D. Evolution of and evolutionary relationships between extant vaccinia virus strains. J Virol. 2015;89:1809-24 pubmed publisher
    ..Based on these findings, it is possible that all existing strains of VACV are derived from a single complex stock of viruses that has been passaged, distributed, and sampled over time. ..
  3. Jesus D, Moussatche N, McFadden B, Nielsen C, D Costa S, Condit R. Vaccinia virus protein A3 is required for the production of normal immature virions and for the encapsidation of the nucleocapsid protein L4. Virology. 2015;481:1-12 pubmed publisher
    ..By characterizing an inducible mutant in the A3L gene, we revealed that A3, an inner core wall protein, is important for formation of normal immature viruses and ..