Gene Symbol: A33R
Description: EEV membrane phosphoglycoprotein
Species: Vaccinia virus
Products:     A33R

Top Publications

  1. Doceul V, Hollinshead M, van der Linden L, Smith G. Repulsion of superinfecting virions: a mechanism for rapid virus spread. Science. 2010;327:873-876 pubmed publisher
    ..Additional spreading mechanisms may exist for other viruses that also spread faster than predicted by replication kinetics. ..
  2. Chan W, Ward B. There is an A33-dependent mechanism for the incorporation of B5-GFP into vaccinia virus extracellular enveloped virions. Virology. 2010;402:83-93 pubmed publisher
    ..To investigate the function of A33, a recombinant virus that has A33R deleted and expresses B5R-GFP (vB5R-GFP/DeltaA33R) was generated...
  3. Krupovic M, Cvirkaite Krupovic V, Bamford D. Protein A33 responsible for antibody-resistant spread of Vaccinia virus is homologous to C-type lectin-like proteins. Virus Res. 2010;151:97-101 pubmed publisher
    ..Our results provide insights into the structure and origin of protein A33. ..
  4. Chan W, Kalkanoglu A, Ward B. The inability of vaccinia virus A33R protein to form intermolecular disulfide-bonded homodimers does not affect the production of infectious extracellular virus. Virology. 2010;408:109-18 pubmed publisher
    ..investigate the role of disulfide-bonded homodimers during viral morphogenesis, recombinant viruses that express an A33R with cysteine 62 mutated to serine were generated...
  5. Breiman A, Carpentier D, Ewles H, Smith G. Transport and stability of the vaccinia virus A34 protein is affected by the A33 protein. J Gen Virol. 2013;94:720-5 pubmed publisher
    ..Thus, A34 requires more than one other EEV protein for its processing and cellular transport. ..
  6. Qin L, Favis N, Famulski J, Evans D. Evolution of and evolutionary relationships between extant vaccinia virus strains. J Virol. 2015;89:1809-24 pubmed publisher
    ..Based on these findings, it is possible that all existing strains of VACV are derived from a single complex stock of viruses that has been passaged, distributed, and sampled over time. ..