Genomes and Genes
Gene Symbol: ttgA
Description: multidrug/solvent efflux RND membrane fusion protein
- Efflux pumps involved in toluene tolerance in Pseudomonas putida DOT-T1EJ L Ramos
Department of Biochemistry and Molecular and Cellular Biology of Plants, Consejo Superior de Investigaciones Cientificas, Granada, Spain
J Bacteriol 180:3323-9. 1998..The mutation in P. putida DOT-T1E-18 was cloned, and the knockedout gene was sequenced and found to be homologous to the drug exclusion gene mexB, which belongs to the efflux pump family of the resistant nodulator division type...
- Three efflux pumps are required to provide efficient tolerance to toluene in Pseudomonas putida DOT-T1EA Rojas
Department of Biochemistry and Molecular and Cell Biology of Plants, Estacion Experimental del Zaidin, CSIC, E 18008 Granada, Spain
J Bacteriol 183:3967-73. 2001..The triple mutant was hypersensitive to toluene, as shown by its inability to grow with toluene supplied via the vapor phase...
- Antibiotic-dependent induction of Pseudomonas putida DOT-T1E TtgABC efflux pump is mediated by the drug binding repressor TtgRWilson Teran
Consejo Superior de Investigaciones Cientificas, Estacion Experimental del Zaidin, Department of Plant Biochemistry, Molecular and Cellular Biology, Granada, Spain
Antimicrob Agents Chemother 47:3067-72. 2003..This is the first case in which the expression of a drug transporter of the resistance-nodulation-division family has been shown to be regulated directly by antibiotics...