Tb927.8.620

Summary

Gene Symbol: Tb927.8.620
Description: RNA-editing complex protein MP42
Alias: Tb08.12O16.180, RNA-editing complex protein MP42
Species: Trypanosoma brucei TREU927

Top Publications

  1. Panigrahi A, Schnaufer A, Carmean N, Igo R, Gygi S, Ernst N, et al. Four related proteins of the Trypanosoma brucei RNA editing complex. Mol Cell Biol. 2001;21:6833-40 pubmed publisher
    ..Recombinant TbMP63 and TbMP52 coimmunoprecipitate. These results indicate that these four proteins are components of the RNA editing complex and that TbMP63 and TbMP52 can interact...
  2. Brecht M, Niemann M, Schl ter E, M ller U, Stuart K, G ringer H. TbMP42, a protein component of the RNA editing complex in African trypanosomes, has endo-exoribonuclease activity. Mol Cell. 2005;17:621-30 pubmed publisher
    ..However, all three activities can be restored by the addition of rTbMP42. Together, the data suggest that TbMP42 contributes both endo- and exoribonuclease activity to the editing reaction cycle...
  3. Guo X, Ernst N, Stuart K. The KREPA3 zinc finger motifs and OB-fold domain are essential for RNA editing and survival of Trypanosoma brucei. Mol Cell Biol. 2008;28:6939-53 pubmed publisher
    ..KREPA3 may function in editosome organization and/or RNA positioning...

Detail Information

Publications3

  1. Panigrahi A, Schnaufer A, Carmean N, Igo R, Gygi S, Ernst N, et al. Four related proteins of the Trypanosoma brucei RNA editing complex. Mol Cell Biol. 2001;21:6833-40 pubmed publisher
    ..Recombinant TbMP63 and TbMP52 coimmunoprecipitate. These results indicate that these four proteins are components of the RNA editing complex and that TbMP63 and TbMP52 can interact...
  2. Brecht M, Niemann M, Schl ter E, M ller U, Stuart K, G ringer H. TbMP42, a protein component of the RNA editing complex in African trypanosomes, has endo-exoribonuclease activity. Mol Cell. 2005;17:621-30 pubmed publisher
    ..However, all three activities can be restored by the addition of rTbMP42. Together, the data suggest that TbMP42 contributes both endo- and exoribonuclease activity to the editing reaction cycle...
  3. Guo X, Ernst N, Stuart K. The KREPA3 zinc finger motifs and OB-fold domain are essential for RNA editing and survival of Trypanosoma brucei. Mol Cell Biol. 2008;28:6939-53 pubmed publisher
    ..KREPA3 may function in editosome organization and/or RNA positioning...