Gene Symbol: Tb927.8.620
Description: RNA-editing complex protein MP42
Alias: Tb08.12O16.180, RNA-editing complex protein MP42
Species: Trypanosoma brucei TREU927
- Panigrahi A, Schnaufer A, Carmean N, Igo R, Gygi S, Ernst N, et al. Four related proteins of the Trypanosoma brucei RNA editing complex. Mol Cell Biol. 2001;21:6833-40 pubmed publisher..Recombinant TbMP63 and TbMP52 coimmunoprecipitate. These results indicate that these four proteins are components of the RNA editing complex and that TbMP63 and TbMP52 can interact...
- Brecht M, Niemann M, Schl ter E, M ller U, Stuart K, G ringer H. TbMP42, a protein component of the RNA editing complex in African trypanosomes, has endo-exoribonuclease activity. Mol Cell. 2005;17:621-30 pubmed publisher..However, all three activities can be restored by the addition of rTbMP42. Together, the data suggest that TbMP42 contributes both endo- and exoribonuclease activity to the editing reaction cycle...
- Guo X, Ernst N, Stuart K. The KREPA3 zinc finger motifs and OB-fold domain are essential for RNA editing and survival of Trypanosoma brucei. Mol Cell Biol. 2008;28:6939-53 pubmed publisher..KREPA3 may function in editosome organization and/or RNA positioning...