Gene Symbol: Tb927.8.4330
Description: small GTP-binding protein Rab11
Alias: Tb08.29H22.590, small GTP-binding protein Rab11
Species: Trypanosoma brucei TREU927
- Jeffries T, Morgan G, Field M. A developmentally regulated rab11 homologue in Trypanosoma brucei is involved in recycling processes. J Cell Sci. 2001;114:2617-26 pubmed..Hence, TbRAB11 is present on endosomal structures that contain recycling cargo molecules and is under developmental regulation, suggesting a role in stage-dependent endocytic processes...
- Pal A, Hall B, Jeffries T, Field M. Rab5 and Rab11 mediate transferrin and anti-variant surface glycoprotein antibody recycling in Trypanosoma brucei. Biochem J. 2003;374:443-51 pubmed..The presence of an efficient mechanism for the removal of IgG bound to the external surface of T. brucei and its subsequent proteolysis within the recycling system suggests a role for this pathway in immune evasion. ..