Tb927.2.6280

Summary

Gene Symbol: Tb927.2.6280
Description: adenosine transporter 2, putative
Alias: 36E18.140, adenosine transporter 2, putative
Species: Trypanosoma brucei TREU927

Top Publications

  1. De Koning H, Jarvis S. Adenosine transporters in bloodstream forms of Trypanosoma brucei brucei: substrate recognition motifs and affinity for trypanocidal drugs. Mol Pharmacol. 1999;56:1162-70 pubmed
    ..4-2.4 microM)...
  2. Sanchez M, Ullman B, Landfear S, Carter N. Cloning and functional expression of a gene encoding a P1 type nucleoside transporter from Trypanosoma brucei. J Biol Chem. 1999;274:30244-9 pubmed
    ..Genomic Southern blots suggest that there are multiple genes related in sequence to TbNT2, implying the existence of a family of nucleoside transporter genes in these parasites. ..
  3. Sanchez M, Tryon R, Green J, Boor I, Landfear S. Six related nucleoside/nucleobase transporters from Trypanosoma brucei exhibit distinct biochemical functions. J Biol Chem. 2002;277:21499-504 pubmed publisher
    ..These results demonstrate that T. brucei expresses multiple purine transporters with distinct substrate specificities and different patterns of expression during the parasite life cycle...

Scientific Experts

Detail Information

Publications3

  1. De Koning H, Jarvis S. Adenosine transporters in bloodstream forms of Trypanosoma brucei brucei: substrate recognition motifs and affinity for trypanocidal drugs. Mol Pharmacol. 1999;56:1162-70 pubmed
    ..4-2.4 microM)...
  2. Sanchez M, Ullman B, Landfear S, Carter N. Cloning and functional expression of a gene encoding a P1 type nucleoside transporter from Trypanosoma brucei. J Biol Chem. 1999;274:30244-9 pubmed
    ..Genomic Southern blots suggest that there are multiple genes related in sequence to TbNT2, implying the existence of a family of nucleoside transporter genes in these parasites. ..
  3. Sanchez M, Tryon R, Green J, Boor I, Landfear S. Six related nucleoside/nucleobase transporters from Trypanosoma brucei exhibit distinct biochemical functions. J Biol Chem. 2002;277:21499-504 pubmed publisher
    ..These results demonstrate that T. brucei expresses multiple purine transporters with distinct substrate specificities and different patterns of expression during the parasite life cycle...