Tb927.2.6150

Summary

Gene Symbol: Tb927.2.6150
Description: adenosine transporter 2
Alias: 36E18.75, adenosine transporter 2
Species: Trypanosoma brucei TREU927

Top Publications

  1. Sanchez M, Ullman B, Landfear S, Carter N. Cloning and functional expression of a gene encoding a P1 type nucleoside transporter from Trypanosoma brucei. J Biol Chem. 1999;274:30244-9 pubmed
    ..Genomic Southern blots suggest that there are multiple genes related in sequence to TbNT2, implying the existence of a family of nucleoside transporter genes in these parasites. ..
  2. De Koning H, Jarvis S. Adenosine transporters in bloodstream forms of Trypanosoma brucei brucei: substrate recognition motifs and affinity for trypanocidal drugs. Mol Pharmacol. 1999;56:1162-70 pubmed
    ..4-2.4 microM)...
  3. Sanchez M, Tryon R, Green J, Boor I, Landfear S. Six related nucleoside/nucleobase transporters from Trypanosoma brucei exhibit distinct biochemical functions. J Biol Chem. 2002;277:21499-504 pubmed publisher
    ..These results demonstrate that T. brucei expresses multiple purine transporters with distinct substrate specificities and different patterns of expression during the parasite life cycle...

Detail Information

Publications3

  1. Sanchez M, Ullman B, Landfear S, Carter N. Cloning and functional expression of a gene encoding a P1 type nucleoside transporter from Trypanosoma brucei. J Biol Chem. 1999;274:30244-9 pubmed
    ..Genomic Southern blots suggest that there are multiple genes related in sequence to TbNT2, implying the existence of a family of nucleoside transporter genes in these parasites. ..
  2. De Koning H, Jarvis S. Adenosine transporters in bloodstream forms of Trypanosoma brucei brucei: substrate recognition motifs and affinity for trypanocidal drugs. Mol Pharmacol. 1999;56:1162-70 pubmed
    ..4-2.4 microM)...
  3. Sanchez M, Tryon R, Green J, Boor I, Landfear S. Six related nucleoside/nucleobase transporters from Trypanosoma brucei exhibit distinct biochemical functions. J Biol Chem. 2002;277:21499-504 pubmed publisher
    ..These results demonstrate that T. brucei expresses multiple purine transporters with distinct substrate specificities and different patterns of expression during the parasite life cycle...