ATP dependent phosphofructokinase
Gene Symbol: ATP dependent phosphofructokinase
Description: ATP-dependent phosphofructokinase
Species: Trypanosoma brucei brucei strain 927/4 GUTat10.1
- The glycosomal ATP-dependent phosphofructokinase of Trypanosoma brucei must have evolved from an ancestral pyrophosphate-dependent enzymeP A Michels
International Institute of Cellular and Molecular Pathology and Laboratory of Biochemistry, Catholic University of Louvain, Brussels, Belgium
Eur J Biochem 250:698-704. 1997..brucei PFK shows many structural differences, even at the active site, when compared with other ATP-dependent PFKs. These differences offer great potential for the structure-based design of trypanocidal drugs...