Gene Symbol: GAD3
Description: glutamate decarboxylase isoform3
Alias: LeGAD3, SlGAD3, glutamate decarboxylase isoform3
Species: tomato

Top Publications

  1. Akihiro T, Koike S, Tani R, Tominaga T, Watanabe S, Iijima Y, et al. Biochemical mechanism on GABA accumulation during fruit development in tomato. Plant Cell Physiol. 2008;49:1378-89 pubmed publisher
    ..During GABA accumulation, we found positive correlations among GABA contents and expression levels of SlGAD2 and SlGAD3. Both of these genes encode glutamate decarboxylase (GAD) which is a key enzyme of GABA biosynthesis...
  2. Takayama M, Koike S, Kusano M, Matsukura C, Saito K, Ariizumi T, et al. Tomato Glutamate Decarboxylase Genes SlGAD2 and SlGAD3 Play Key Roles in Regulating γ-Aminobutyric Acid Levels in Tomato (Solanum lycopersicum). Plant Cell Physiol. 2015;56:1533-45 pubmed publisher
    ..We previously identified three tomato genes (SlGAD1, SlGAD2 and SlGAD3) encoding glutamate decarboxylase (GAD), likely the key enzyme for GABA biosynthesis in tomato fruits...
  3. Takayama M, Matsukura C, Ariizumi T, Ezura H. Activating glutamate decarboxylase activity by removing the autoinhibitory domain leads to hyper ?-aminobutyric acid (GABA) accumulation in tomato fruit. Plant Cell Rep. 2017;36:103-116 pubmed publisher
    The C-terminal extension region of SlGAD3 is likely involved in autoinhibition, and removing this domain increases GABA levels in tomato fruits...

Scientific Experts