Gene Symbol: YUC6
Description: Flavin-binding monooxygenase family protein
Alias: AtYUC6, T14C9.160, T14C9_160, YUCCA6, Flavin-binding monooxygenase family protein
Species: thale cress

Top Publications

  1. Cheng Y, Dai X, Zhao Y. Auxin biosynthesis by the YUCCA flavin monooxygenases controls the formation of floral organs and vascular tissues in Arabidopsis. Genes Dev. 2006;20:1790-9 pubmed
    ..gene family and show unequivocally that four of the 11 predicted YUC flavin monooxygenases (YUC1, YUC2, YUC4, and YUC6) play essential roles in auxin biosynthesis and plant development...
  2. Kim J, Sharkhuu A, Jin J, Li P, Jeong J, Baek D, et al. yucca6, a dominant mutation in Arabidopsis, affects auxin accumulation and auxin-related phenotypes. Plant Physiol. 2007;145:722-35 pubmed
    ..Here, we report the discovery of fertile dominant Arabidopsis hypertall1-1D and hypertall1-2D (yucca6-1D, -2D) mutants that exhibit typical auxin overproduction phenotypic alterations, such as epinastic cotyledons, ..
  3. Cha J, Kim W, Kang S, Kim J, Baek D, Jung I, et al. A novel thiol-reductase activity of Arabidopsis YUC6 confers drought tolerance independently of auxin biosynthesis. Nat Commun. 2015;6:8041 pubmed publisher
    ..Here we report that Arabidopsis plants overexpressing YUC6 display enhanced IAA-related phenotypes and exhibit improved drought stress tolerance, low rate of water loss and ..
  4. Li L, Qin G, Tsuge T, Hou X, Ding M, Aoyama T, et al. SPOROCYTELESS modulates YUCCA expression to regulate the development of lateral organs in Arabidopsis. New Phytol. 2008;179:751-64 pubmed publisher
    ..Interestingly, the expression of YUC2 and YUC6, two key genes in auxin biosynthesis, was significantly repressed in spl-D plants...
  5. Kim J, Murphy A, Baek D, Lee S, Yun D, Bressan R, et al. YUCCA6 over-expression demonstrates auxin function in delaying leaf senescence in Arabidopsis thaliana. J Exp Bot. 2011;62:3981-92 pubmed publisher
    ..A YUCCA6 activation mutant, yuc6-1D, has been shown to contain an elevated free IAA level and to display typical high-auxin ..
  6. Kang B, Wang H, Nam K, Li J, Li J. Activation-tagged suppressors of a weak brassinosteroid receptor mutant. Mol Plant. 2010;3:260-8 pubmed publisher
    ..Further studies of these atbs-D mutants could lead to better understanding of the BR signaling process and the BR-auxin interaction. ..
  7. Dai X, Mashiguchi K, Chen Q, Kasahara H, Kamiya Y, Ojha S, et al. The biochemical mechanism of auxin biosynthesis by an arabidopsis YUCCA flavin-containing monooxygenase. J Biol Chem. 2013;288:1448-57 pubmed publisher
    ..Here we present the biochemical characterization of recombinant Arabidopsis YUC6. Expressed in and purified from Escherichia coli, YUC6 contains FAD as a cofactor, which has peaks at 448 nm and ..
  8. Kim J, Baek D, Park H, Chun H, Oh D, Lee M, et al. Overexpression of Arabidopsis YUCCA6 in potato results in high-auxin developmental phenotypes and enhanced resistance to water deficit. Mol Plant. 2013;6:337-49 pubmed publisher
    ..Transgenic potato (Solanum tuberosum cv. Jowon) constitutively overexpressing Arabidopsis AtYUC6 displayed high-auxin phenotypes such as narrow downward-curled leaves, increased height, erect stature, and ..
  9. Cheol Park H, Cha J, Yun D. Roles of YUCCAs in auxin biosynthesis and drought stress responses in plants. Plant Signal Behav. 2013;8:e24495 pubmed publisher
    ..Transgenic potato (Solanum tuberosum cv. Jowon) overexpressing AtYUC6 showed high-auxin and enhanced drought tolerance phenotypes...

More Information


  1. Ke Q, Wang Z, Ji C, Jeong J, Lee H, Li H, et al. Transgenic poplar expressing Arabidopsis YUCCA6 exhibits auxin-overproduction phenotypes and increased tolerance to abiotic stress. Plant Physiol Biochem. 2015;94:19-27 pubmed publisher
    b>YUCCA6, a member of the YUCCA family of flavin monooxygenase-like proteins, is involved in the tryptophan-dependent IAA biosynthesis pathway and responses to environmental cues in Arabidopsis...