XYLT

Summary

Gene Symbol: XYLT
Description: beta-1,2-xylosyltransferase
Alias: ''beta-1, 2-XYLOSYLTRANSFERASE, 2-xylosyltransferase, 2-xylosyltransferase'', ARABIDOPSIS THALIANA BETA-1, ATXYLT, beta-1, beta-1,2-xylosyltransferase
Species: thale cress

Top Publications

  1. Strasser R, Mucha J, Mach L, Altmann F, Wilson I, Glössl J, et al. Molecular cloning and functional expression of beta1, 2-xylosyltransferase cDNA from Arabidopsis thaliana. FEBS Lett. 2000;472:105-8 pubmed
    ..xylose from UDP-xylose to the core beta-linked mannose of N-linked oligosaccharides by beta1,2-xylosyltransferase (XylT) is a widespread feature of plant glycoproteins which renders them immunogenic and allergenic in man...
  2. Bencur P, Steinkellner H, Svoboda B, Mucha J, Strasser R, Kolarich D, et al. Arabidopsis thaliana beta1,2-xylosyltransferase: an unusual glycosyltransferase with the potential to act at multiple stages of the plant N-glycosylation pathway. Biochem J. 2005;388:515-25 pubmed
    b>XylT (beta1,2-xylosyltransferase) is a unique Golgi-bound glycosyltransferase that is involved in the biosynthesis of glycoprotein-bound N-glycans in plants...
  3. Dirnberger D, Bencur P, Mach L, Steinkellner H. The Golgi localization of Arabidopsis thaliana beta1,2-xylosyltransferase in plant cells is dependent on its cytoplasmic and transmembrane sequences. Plant Mol Biol. 2002;50:273-81 pubmed
    ..the targeting of proteins to the plant Golgi we studied Arabidopsis thaliana beta1,2-xylosyltransferase (XylT), a glycosyltransferase which is unique to plants and some invertebrates...
  4. Pagny S, Bouissonnie F, Sarkar M, Follet Gueye M, Driouich A, Schachter H, et al. Structural requirements for Arabidopsis beta1,2-xylosyltransferase activity and targeting to the Golgi. Plant J. 2003;33:189-203 pubmed
    Characterization of a beta1,2-xylosyltransferase from Arabidopsis thaliana (AtXylT) was carried out by expression in Sf9 insect cells using a baculovirus vector system...
  5. Kajiura H, Okamoto T, Misaki R, Matsuura Y, Fujiyama K. Arabidopsis ?1,2-xylosyltransferase: substrate specificity and participation in the plant-specific N-glycosylation pathway. J Biosci Bioeng. 2012;113:48-54 pubmed publisher
    ..the plant N-glycosylation pathway, we examined the acceptor substrate specificity of recombinant Arabidopsis XYLT (AtXYLT) using 2-aminopyridine-labeled N-glycans as the substrates and confirmed the N-glycans of Arabidopsis xylt mutant...
  6. Schoberer J, Liebminger E, Botchway S, Strasser R, Hawes C. Time-resolved fluorescence imaging reveals differential interactions of N-glycan processing enzymes across the Golgi stack in planta. Plant Physiol. 2013;161:1737-54 pubmed publisher
  7. Bakker H, Rouwendal G, Karnoup A, Florack D, Stoopen G, Helsper J, et al. An antibody produced in tobacco expressing a hybrid beta-1,4-galactosyltransferase is essentially devoid of plant carbohydrate epitopes. Proc Natl Acad Sci U S A. 2006;103:7577-82 pubmed
    ..Hence, a transgenic plant expressing the hybrid GalT might yield more effective and safer monoclonals for therapeutic purposes than WT plants and even transgenic plants expressing the unchanged GalT. ..