Gene Symbol: XYLT
Alias: ''beta-1, 2-XYLOSYLTRANSFERASE, 2-xylosyltransferase, 2-xylosyltransferase'', ARABIDOPSIS THALIANA BETA-1, ATXYLT, beta-1, beta-1,2-xylosyltransferase
Species: thale cress
Strasser R, Mucha J, Mach L, Altmann F, Wilson I, Glössl J, et al
. Molecular cloning and functional expression of beta1, 2-xylosyltransferase cDNA from Arabidopsis thaliana. FEBS Lett. 2000;472:105-8 pubmed
..xylose from UDP-xylose to the core beta-linked mannose of N-linked oligosaccharides by beta1,2-xylosyltransferase (XylT) is a widespread feature of plant glycoproteins which renders them immunogenic and allergenic in man...
Bencur P, Steinkellner H, Svoboda B, Mucha J, Strasser R, Kolarich D, et al
. Arabidopsis thaliana beta1,2-xylosyltransferase: an unusual glycosyltransferase with the potential to act at multiple stages of the plant N-glycosylation pathway. Biochem J. 2005;388:515-25 pubmed
b>XylT (beta1,2-xylosyltransferase) is a unique Golgi-bound glycosyltransferase that is involved in the biosynthesis of glycoprotein-bound N-glycans in plants...
Dirnberger D, Bencur P, Mach L, Steinkellner H. The Golgi localization of Arabidopsis thaliana beta1,2-xylosyltransferase in plant cells is dependent on its cytoplasmic and transmembrane sequences. Plant Mol Biol. 2002;50:273-81 pubmed
..the targeting of proteins to the plant Golgi we studied Arabidopsis thaliana beta1,2-xylosyltransferase (XylT), a glycosyltransferase which is unique to plants and some invertebrates...
Pagny S, Bouissonnie F, Sarkar M, Follet Gueye M, Driouich A, Schachter H, et al
. Structural requirements for Arabidopsis beta1,2-xylosyltransferase activity and targeting to the Golgi. Plant J. 2003;33:189-203 pubmed
Characterization of a beta1,2-xylosyltransferase from Arabidopsis thaliana (AtXylT) was carried out by expression in Sf9 insect cells using a baculovirus vector system...
Kajiura H, Okamoto T, Misaki R, Matsuura Y, Fujiyama K. Arabidopsis ?1,2-xylosyltransferase: substrate specificity and participation in the plant-specific N-glycosylation pathway. J Biosci Bioeng. 2012;113:48-54 pubmed publisher
..the plant N-glycosylation pathway, we examined the acceptor substrate specificity of recombinant Arabidopsis XYLT (AtXYLT) using 2-aminopyridine-labeled N-glycans as the substrates and confirmed the N-glycans of Arabidopsis xylt mutant...
Schoberer J, Liebminger E, Botchway S, Strasser R, Hawes C. Time-resolved fluorescence imaging reveals differential interactions of N-glycan processing enzymes across the Golgi stack in planta. Plant Physiol. 2013;161:1737-54 pubmed publisher
Bakker H, Rouwendal G, Karnoup A, Florack D, Stoopen G, Helsper J, et al
. An antibody produced in tobacco expressing a hybrid beta-1,4-galactosyltransferase is essentially devoid of plant carbohydrate epitopes. Proc Natl Acad Sci U S A. 2006;103:7577-82 pubmed
..Hence, a transgenic plant expressing the hybrid GalT might yield more effective and safer monoclonals for therapeutic purposes than WT plants and even transgenic plants expressing the unchanged GalT. ..