Gene Symbol: WSIP2
Description: WUS-interacting protein 2
Alias: TOPLESS-RELATED 4, TPR4, WUS-interacting protein 2, WUS-interacting protein 2
Species: thale cress

Top Publications

  1. Kieffer M, Stern Y, Cook H, Clerici E, Maulbetsch C, Laux T, et al. Analysis of the transcription factor WUSCHEL and its functional homologue in Antirrhinum reveals a potential mechanism for their roles in meristem maintenance. Plant Cell. 2006;18:560-73 pubmed
    ..Our results suggest that WUS functions by recruiting transcriptional corepressors to repress target genes that promote differentiation, thereby ensuring stem cell maintenance...
  2. Long J, Ohno C, Smith Z, Meyerowitz E. TOPLESS regulates apical embryonic fate in Arabidopsis. Science. 2006;312:1520-3 pubmed
    ..These data point to a transcriptional repression mechanism that prevents root formation in the shoot pole during Arabidopsis embryogenesis. ..
  3. Oh E, Zhu J, Ryu H, Hwang I, Wang Z. TOPLESS mediates brassinosteroid-induced transcriptional repression through interaction with BZR1. Nat Commun. 2014;5:4140 pubmed publisher
    ..The EAR motif in BZR1 mediates recruitment of TPL to BZR1-repressed promoters. A triple tpl mutant (tpl;tpr1;tpr4) shows reduced BR sensitivity and suppresses the gain-of-function bzr1-1D mutant phenotype...
  4. Chen G, Sun J, Liu M, Liu J, Yang W. SPOROCYTELESS is a novel embryophyte-specific transcription repressor that interacts with TPL and TCP proteins in Arabidopsis. J Genet Genomics. 2014;41:617-25 pubmed publisher
    ..Together, we propose that SPL and SPEARs most likely belong to a novel transcription repressor family in land plants which may play a variety of developmental roles in plants. ..
  5. Wei B, Zhang J, Pang C, Yu H, Guo D, Jiang H, et al. The molecular mechanism of sporocyteless/nozzle in controlling Arabidopsis ovule development. Cell Res. 2015;25:121-34 pubmed publisher
    ..Our findings suggest that a similar gene repression strategy is employed by both plants and fungi to control sporogenesis. ..