Gene Symbol: WNK8
Description: with no lysine (K) kinase 8
Alias: ATWNK8, EIP1, EMF1-Interacting Protein 1, MJC20.9, MJC20_9, with no lysine (K) kinase 8, with no lysine (K) kinase 8
Species: thale cress
Tsuchiya T, Eulgem T. The Arabidopsis defense component EDM2 affects the floral transition in an FLC-dependent manner. Plant J. 2010;62:518-28 pubmed publisher
..We further found that the protein kinase WNK8 physically interacts with EDM2 in the nucleus...
Hong Hermesdorf A, Brüx A, Grüber A, Gruber G, Schumacher K. A WNK kinase binds and phosphorylates V-ATPase subunit C. FEBS Lett. 2006;580:932-9 pubmed
..Here, we report that a member of the Arabidopsis WNK family (AtWNK8) interacts with subunit C of the vacuolar H+-ATPase (V-ATPase) via a short C-terminal domain...
Urano D, Phan N, Jones J, Yang J, Huang J, GRIGSTON J, et al
. Endocytosis of the seven-transmembrane RGS1 protein activates G-protein-coupled signalling in Arabidopsis. Nat Cell Biol. 2012;14:1079-88 pubmed publisher
..Phosphorylation of AtRGS1 by AtWNK8 kinase causes AtRGS1 endocytosis, required for both G-protein-mediated sugar signalling and cell proliferation...
Park H, Lee S, Seok H, Kim S, Sung Z, Moon Y. EMF1 interacts with EIP1, EIP6 or EIP9 involved in the regulation of flowering time in Arabidopsis. Plant Cell Physiol. 2011;52:1376-88 pubmed publisher
..Among the candidate genes, three EMF1-Interacting Protein (EIP) genes, EIP1, EIP6 and EIP9, are predicted to encode a WNK (with-no-lysine) kinase, a B-box zinc-finger protein and a DnaJ-..
Wang Y, Liu K, Liao H, Zhuang C, Ma H, Yan X. The plant WNK gene family and regulation of flowering time in Arabidopsis. Plant Biol (Stuttg). 2008;10:548-62 pubmed publisher
..T-DNA knockout mutations in the AtWNK2, AtWNK5 and AtWNK8 genes in different phylogenetic clades caused early flowering...
Zhang B, Liu K, Zheng Y, Wang Y, Wang J, Liao H. Disruption of AtWNK8 enhances tolerance of Arabidopsis to salt and osmotic stresses via modulating proline content and activities of catalase and peroxidase. Int J Mol Sci. 2013;14:7032-47 pubmed publisher
..However, its role in salt and osmotic stress tolerance is unclear. Here, we report that AtWNK8 is mainly expressed in primary root, hypocotyl, stamen and pistil and is induced by NaCl and sorbitol treatment...
Urano D, Czarnecki O, Wang X, Jones A, Chen J. Arabidopsis receptor of activated C kinase1 phosphorylation by WITH NO LYSINE8 KINASE. Plant Physiol. 2015;167:507-16 pubmed publisher
..Here, we show that an atypical serine (Ser)/threonine (Thr) protein kinase, WITH NO LYSINE8 (WNK8), phosphorylates RACK1...
Nakamichi N, Murakami Kojima M, Sato E, Kishi Y, Yamashino T, Mizuno T. Compilation and characterization of a novel WNK family of protein kinases in Arabiodpsis thaliana with reference to circadian rhythms. Biosci Biotechnol Biochem. 2002;66:2429-36 pubmed
..These results suggested that certain members of the WNK family of protein kinases might play roles in a mechanism that generates circadian rhythms in Arabidopsis. ..
Tsuchiya T, Eulgem T. Co-option of EDM2 to distinct regulatory modules in Arabidopsis thaliana development. BMC Plant Biol. 2010;10:203 pubmed publisher
..function of EDM2, but not its role in RPP7-mediated disease resistance, seems to involve the protein kinase WNK8, which physically interacts with EDM2 in nuclei...