Gene Symbol: VRN2
Description: VEFS-Box of polycomb protein
Alias: REDUCED VERNALIZATION RESPONSE 2, VEFS-Box of polycomb protein
Species: thale cress
Jullien P, Katz A, Oliva M, Ohad N, Berger F. Polycomb group complexes self-regulate imprinting of the Polycomb group gene MEDEA in Arabidopsis. Curr Biol. 2006;16:486-92 pubmed
..This feedback loop ensures a complete maternal control of MEA expression from both parental alleles and might have provided a template for evolution of imprinting in plants. ..
Chanvivattana Y, Bishopp A, Schubert D, Stock C, Moon Y, Sung Z, et al
. Interaction of Polycomb-group proteins controlling flowering in Arabidopsis. Development. 2004;131:5263-76 pubmed
In Arabidopsis, the EMBYRONIC FLOWER2 (EMF2), VERNALISATION2 (VRN2) and FERTILISATION INDEPENDENT ENDOSPERM2 (FIS2) genes encode related Polycomb-group (Pc-G) proteins...
Wood C, Robertson M, Tanner G, Peacock W, Dennis E, Helliwell C. The Arabidopsis thaliana vernalization response requires a polycomb-like protein complex that also includes VERNALIZATION INSENSITIVE 3. Proc Natl Acad Sci U S A. 2006;103:14631-6 pubmed
..epigenetic repression of FLC expression, a process that requires the polycomb group (PcG) protein VERNALIZATION 2 (VRN2) and the plant homeodomain protein VERNALIZATION INSENSITIVE 3 (VIN3)...
Derkacheva M, Steinbach Y, Wildhaber T, Mozgová I, Mahrez W, Nanni P, et al
. Arabidopsis MSI1 connects LHP1 to PRC2 complexes. EMBO J. 2013;32:2073-85 pubmed publisher
..The LHP1-MSI1 interaction forms a positive feedback loop to recruit PRC2 to chromatin that carries H3K27me3. Consequently, this can provide a mechanism for the faithful inheritance of local epigenetic information through replication. ..
Chandler J, Wilson A, Dean C. Arabidopsis mutants showing an altered response to vernalization. Plant J. 1996;10:637-44 pubmed
..The vrn1 and vrn2 mutations did not affect the acclimation response as judged by expression of cold-induced transcripts and freezing ..
De Lucia F, Crevillen P, Jones A, Greb T, Dean C. A PHD-polycomb repressive complex 2 triggers the epigenetic silencing of FLC during vernalization. Proc Natl Acad Sci U S A. 2008;105:16831-6 pubmed publisher
..been shown to require conserved Polycomb Repressive Complex 2 (PRC2) components including the Su(z)12 homologue, VRN2, and two plant homeodomain (PHD) finger proteins, VRN5 and VIN3...
Gendall A, Levy Y, Wilson A, Dean C. The VERNALIZATION 2 gene mediates the epigenetic regulation of vernalization in Arabidopsis. Cell. 2001;107:525-35 pubmed
..The VERNALIZATION2 (VRN2) gene mediates vernalization and encodes a nuclear-localized zinc finger protein with similarity to Polycomb group (..
Hecker A, Brand L, Peter S, Simoncello N, Kilian J, Harter K, et al
. The Arabidopsis GAGA-Binding Factor BASIC PENTACYSTEINE6 Recruits the POLYCOMB-REPRESSIVE COMPLEX1 Component LIKE HETEROCHROMATIN PROTEIN1 to GAGA DNA Motifs. Plant Physiol. 2015;168:1013-24 pubmed publisher
..BPC6) interacts with like heterochromatin protein1 (LHP1), a PRC1 component, and associates with vernalization2 (VRN2), a PRC2 component, in vivo...
Liang S, Hartwig B, Perera P, Mora GarcÃa S, de Leau E, Thornton H, et al
. Kicking against the PRCs - A Domesticated Transposase Antagonises Silencing Mediated by Polycomb Group Proteins and Is an Accessory Component of Polycomb Repressive Complex 2. PLoS Genet. 2015;11:e1005660 pubmed publisher