Gene Symbol: VIN3
Description: Fibronectin type III domain-containing protein
Alias: MSF19.4, MSF19_4, VERNALIZATION INSENSITIVE 3, Fibronectin type III domain-containing protein
Species: thale cress

Top Publications

  1. Wood C, Robertson M, Tanner G, Peacock W, Dennis E, Helliwell C. The Arabidopsis thaliana vernalization response requires a polycomb-like protein complex that also includes VERNALIZATION INSENSITIVE 3. Proc Natl Acad Sci U S A. 2006;103:14631-6 pubmed
    ..that requires the polycomb group (PcG) protein VERNALIZATION 2 (VRN2) and the plant homeodomain protein VERNALIZATION INSENSITIVE 3 (VIN3)...
  2. Bond D, Dennis E, Pogson B, Finnegan E. Histone acetylation, VERNALIZATION INSENSITIVE 3, FLOWERING LOCUS C, and the vernalization response. Mol Plant. 2009;2:724-737 pubmed publisher
    The quantitative induction of VIN3 by low temperatures is required for PRC2 repression of FLC and promotion of flowering (vernalization) in Arabidopsis...
  3. Bond D, Wilson I, Dennis E, Pogson B, Jean Finnegan E. VERNALIZATION INSENSITIVE 3 (VIN3) is required for the response of Arabidopsis thaliana seedlings exposed to low oxygen conditions. Plant J. 2009;59:576-87 pubmed publisher
    b>VERNALIZATION INSENSITIVE 3 (VIN3), which is required for the vernalization-mediated epigenetic repression of FLOWERING LOCUS C (FLC) in Arabidopsis thaliana, is quantitatively induced in response to low temperatures...
  4. Sung S, Schmitz R, Amasino R. A PHD finger protein involved in both the vernalization and photoperiod pathways in Arabidopsis. Genes Dev. 2006;20:3244-8 pubmed
    ..In the vernalization pathway, VIL1, along with VERNALIZATION INSENSITIVE 3 (VIN3), is necessary for the modifications to FLC and FLM chromatin that are associated with an ..
  5. Greb T, Mylne J, Crevillen P, Geraldo N, An H, Gendall A, et al. The PHD finger protein VRN5 functions in the epigenetic silencing of Arabidopsis FLC. Curr Biol. 2007;17:73-8 pubmed Arabidopsis, cold temperatures repress FLOWERING LOCUS C (FLC) expression in a mechanism involving VERNALIZATION INSENSITIVE 3 (VIN3), and this repression is epigenetically maintained by a Polycomb-like chromatin regulation ..
  6. De Lucia F, Crevillen P, Jones A, Greb T, Dean C. A PHD-polycomb repressive complex 2 triggers the epigenetic silencing of FLC during vernalization. Proc Natl Acad Sci U S A. 2008;105:16831-6 pubmed publisher
    ..PRC2) components including the Su(z)12 homologue, VRN2, and two plant homeodomain (PHD) finger proteins, VRN5 and VIN3. However, the sequence of events leading to FLC repression was unclear...
  7. Sung S, Amasino R. Vernalization in Arabidopsis thaliana is mediated by the PHD finger protein VIN3. Nature. 2004;427:159-64 pubmed
    ..Here we identify a gene with a function in the measurement of the duration of cold exposure and in the establishment of the vernalized state. We show that this silencing involves changes in the modification of histones in FLC chromatin. ..
  8. Kim D, Sung S. The Binding Specificity of the PHD-Finger Domain of VIN3 Moderates Vernalization Response. Plant Physiol. 2017;173:1258-1268 pubmed publisher
    Vernalization is a response to winter cold to initiate flowering in spring. VERNALIZATION INSENSITIVE3 (VIN3) is induced by winter cold and is essential to vernalization response in Arabidopsis (Arabidopsis thaliana)...
  9. Kim D, Zografos B, Sung S. Vernalization-mediated VIN3 Induction Overcomes the LIKE-HETEROCHROMATIN PROTEIN1/POLYCOMB REPRESSION COMPLEX2-mediated epigenetic repression. Plant Physiol. 2010;154:949-57 pubmed publisher
    VERNALIZATION INSENSITIVE3 (VIN3) induction by vernalization is one of the earliest events in the vernalization response of Arabidopsis (Arabidopsis thaliana)...

More Information


  1. Kim D, Zografos B, Sung S. Mechanisms underlying vernalization-mediated VIN3 induction in Arabidopsis. Plant Signal Behav. 2010;5:1457-9 pubmed publisher
    b>VERNALIZATION INSENSITIVE 3 (VIN3) is required for vernalization-mediated repression of FLOWERING LOCUS C (FLC) in Arabidopsis. The induction of VIN3 by long-term exposure to cold is one of earliest events in vernalization response...
  2. Kim D, Sung S. Coordination of the vernalization response through a VIN3 and FLC gene family regulatory network in Arabidopsis. Plant Cell. 2013;25:454-69 pubmed publisher
    ..In Arabidopsis thaliana, VERNALIZATION INSENSITIVE3 (VIN3) and its related plant homeodomain finger proteins act together with Polycomb Repressive Complex 2 to increase ..