Gene Symbol: VIM3
Description: Zinc finger (C3HC4-type RING finger) family protein
Alias: MIJ24.3, MIJ24_3, ORTH1, ORTHRUS 1, VARIANT IN METHYLATION 3, Zinc finger (C3HC4-type RING finger) family protein
Species: thale cress

Top Publications

  1. Johnson L, Bostick M, Zhang X, Kraft E, Henderson I, Callis J, et al. The SRA methyl-cytosine-binding domain links DNA and histone methylation. Curr Biol. 2007;17:379-84 pubmed
    ..Hence, unlike the methyl-binding domain (MBD), which binds only methylated-CpG sequences, the SRA domain is a versatile new methyl-DNA-binding motif. ..
  2. Woo H, Pontes O, Pikaard C, Richards E. VIM1, a methylcytosine-binding protein required for centromeric heterochromatinization. Genes Dev. 2007;21:267-77 pubmed
    ..VIM1 associates with methylated genomic loci in vivo and is enriched in chromocenters. Our findings suggest that VIM1 acts at the DNA methylation-histone interface to maintain centromeric heterochromatin. ..
  3. Shook M, Richards E. VIM proteins regulate transcription exclusively through the MET1 cytosine methylation pathway. Epigenetics. 2014;9:980-6 pubmed publisher
    ..In this study, we used RNA-seq analysis to profile the transcriptomes of vim1, vim1 vim2 vim3, and met1 null mutants...
  4. Kraft E, Bostick M, Jacobsen S, Callis J. ORTH/VIM proteins that regulate DNA methylation are functional ubiquitin E3 ligases. Plant J. 2008;56:704-15 pubmed publisher
    ..b>ORTH1- ORTH5 are predicted to encode proteins that contain one plant homeodomain (PHD), two really interesting new gene (..
  5. Woo H, Dittmer T, Richards E. Three SRA-domain methylcytosine-binding proteins cooperate to maintain global CpG methylation and epigenetic silencing in Arabidopsis. PLoS Genet. 2008;4:e1000156 pubmed publisher
    ..The vim1 vim3 double mutant and the transgenic vim knock-down lines showed decreased DNA methylation primarily at CpG sites in ..