Gene Symbol: UVH6
Description: RAD3-like DNA-binding helicase protein
Alias: ARABIDOPSIS THALIANA XERODERMA PIGMENTOSUM GROUP D, ATXPD, ULTRAVIOLET HYPERSENSITIVE 6, RAD3-like DNA-binding helicase protein
Species: thale cress
Larkindale J, Hall J, Knight M, Vierling E. Heat stress phenotypes of Arabidopsis mutants implicate multiple signaling pathways in the acquisition of thermotolerance. Plant Physiol. 2005;138:882-97 pubmed
..g. fatty acid desaturase mutants, uvh6)...
Jenkins M, Suzuki T, Mount D. Evidence that heat and ultraviolet radiation activate a common stress-response program in plants that is altered in the uvh6 mutant of Arabidopsis thaliana. Plant Physiol. 1997;115:1351-8 pubmed
The uvh6 mutant of Arabidopsis was previously isolated in a screen for increased sensitivity to ultraviolet (UV) radiation. uvh6 mutant plants were killed by incubation at 37 degrees C for 4 d, a treatment not lethal to wild-type plants...
Liu Z, Hong S, Escobar M, Vierling E, Mitchell D, Mount D, et al
. Arabidopsis UVH6, a homolog of human XPD and yeast RAD3 DNA repair genes, functions in DNA repair and is essential for plant growth. Plant Physiol. 2003;132:1405-14 pubmed
..We have mapped the uvh6-1 locus to chromosome I and have identified a candidate gene, AtXPD, within the corresponding region...
Ly V, Hatherell A, Kim E, Chan A, Belmonte M, Schroeder D. Interactions between Arabidopsis DNA repair genes UVH6, DDB1A, and DDB2 during abiotic stress tolerance and floral development. Plant Sci. 2013;213:88-97 pubmed publisher
..Damaged DNA binding protein 1A (DDB1A), DDB2, and UV hypersensitive 6 (UVH6)/XPD are all involved in the repair of UV-damaged DNA - DDB1A and DDB2 in the initial damage recognition stage, ..
Bilichak A, Yao Y, Titov V, Golubov A, Kovalchuk I. Genome stability in the uvh6 mutant of Arabidopsis thaliana. Plant Cell Rep. 2014;33:979-91 pubmed publisher
Plant XPD homolog UVH6 is the protein involved in the repair of strand breaks, and the excision repair and uvh6 mutant is not impaired in transgenerational increase in HRF...
Vonarx E, Tabone E, Osmond M, Anderson H, Kunz B. Arabidopsis homologue of human transcription factor IIH/nucleotide excision repair factor p44 can function in transcription and DNA repair and interacts with AtXPD. Plant J. 2006;46:512-21 pubmed
..Here we address the capabilities of Arabidopsis thaliana AtGTF2H2 and AtXPD, homologues of the essential interacting human/yeast TFIIH components p44/Ssl1 and XPD/Rad3, respectively...
Kim E, Ly V, Hatherell A, Schroeder D. Genetic interactions between Arabidopsis DET1 and UVH6 during development and abiotic stress response. G3 (Bethesda). 2012;2:913-20 pubmed publisher
..UV-HYPERSENSITIVE 6 (UVH6) mutants are UV and heat sensitive, as well as dwarf and pale, like det1...