Gene Symbol: UBC9
Description: ubiquitin conjugating enzyme 9
Alias: T13J8.70, T13J8_70, UBIQUITIN-PROTEIN LIGASE, ubiquitin conjugating enzyme 9, ubiquitin conjugating enzyme 9
Species: thale cress
Yanagawa Y, Sullivan J, Komatsu S, Gusmaroli G, Suzuki G, Yin J, et al
. Arabidopsis COP10 forms a complex with DDB1 and DET1 in vivo and enhances the activity of ubiquitin conjugating enzymes. Genes Dev. 2004;18:2172-81 pubmed
..Thus, the CDD complex may act as a ubiquitylation-promoting factor to regulate photomorphogenesis. ..
Kraft E, Stone S, Ma L, Su N, Gao Y, Lau O, et al
. Genome analysis and functional characterization of the E2 and RING-type E3 ligase ubiquitination enzymes of Arabidopsis. Plant Physiol. 2005;139:1597-611 pubmed
..This study demonstrates that E2 diversity includes examples with broad and narrow specificity toward RINGs, and that most ubiquitin E2s are broadly expressed with each having a unique spatial and developmental pattern of expression. ..
Luo J, Shen G, Yan J, He C, Zhang H. AtCHIP functions as an E3 ubiquitin ligase of protein phosphatase 2A subunits and alters plant response to abscisic acid treatment. Plant J. 2006;46:649-57 pubmed
..These data suggest that the E3 ubiquitin ligase AtCHIP may function upstream of PP2A in stress-responsive signal transduction pathways under conditions of low temperature or in the dark. ..
Lau O, Deng X. Effect of Arabidopsis COP10 ubiquitin E2 enhancement activity across E2 families and functional conservation among its canonical homologues. Biochem J. 2009;418:683-90 pubmed publisher
..Therefore COP10, despite being a catalytically inactive E2, might still enhance a variety of E2s and regulate numerous aspects of plant development. ..
Dowil R, Lu X, Saracco S, Vierstra R, Downes B. Arabidopsis membrane-anchored ubiquitin-fold (MUB) proteins localize a specific subset of ubiquitin-conjugating (E2) enzymes to the plasma membrane. J Biol Chem. 2011;286:14913-21 pubmed publisher
..These findings suggest that MUBs contribute subcellular specificity to ubiquitylation by docking the conjugation machinery to the plasma membrane. ..