TTG1

Summary

Gene Symbol: TTG1
Description: protein TRANSPARENT TESTA GLABRA 1
Alias: ATTTG1, K18P6.4, K18P6_4, TRANSPARENT TESTA GLABRA 1, TTG, UNARMED 23, URM23
Species: thale cress

Top Publications

  1. ncbi The TTG gene is required to specify epidermal cell fate and cell patterning in the Arabidopsis root
    M E Galway
    Department of Biology, University of Michigan, Ann Arbor 48109
    Dev Biol 166:740-54. 1994
  2. doi The TTG1-bHLH-MYB complex controls trichome cell fate and patterning through direct targeting of regulatory loci
    Mingzhe Zhao
    Section of Molecular Cell and Developmental Biology and The Institute for Cellular and Molecular Biology, The University of Texas at Austin, 2500 Speedway, Austin, TX 78712, USA
    Development 135:1991-9. 2008
  3. ncbi TT8 controls its own expression in a feedback regulation involving TTG1 and homologous MYB and bHLH factors, allowing a strong and cell-specific accumulation of flavonoids in Arabidopsis thaliana
    Antoine Baudry
    Seed Biology Laboratory, UMR 204 INRA INAPG, Jean Pierre Bourgin Institute, Route de Saint Cyr, 78026 Versailles Cedex, France
    Plant J 46:768-79. 2006
  4. pmc Functional specialization of the TRANSPARENT TESTA GLABRA1 network allows differential hormonal control of laminal and marginal trichome initiation in Arabidopsis rosette leaves
    Lies Maes
    Department of Plant Systems Biology, Flanders Institute for Biotechnology, Ghent University, 9052 Ghent, Belgium
    Plant Physiol 148:1453-64. 2008
  5. ncbi Functional diversification of MYB23 and GL1 genes in trichome morphogenesis and initiation
    Victor Kirik
    Botanical Institute, University of Cologne, Gyrhofstrasse 15, 50931 Cologne, Germany
    Development 132:1477-85. 2005
  6. ncbi A contradictory GLABRA3 allele helps define gene interactions controlling trichome development in Arabidopsis
    Jeffrey J Esch
    Department of Plant Biology, University of Minnesota, St Paul, MN 55108 1095, USA
    Development 130:5885-94. 2003
  7. ncbi A network of redundant bHLH proteins functions in all TTG1-dependent pathways of Arabidopsis
    Fan Zhang
    Molecular Cell and Developmental Biology, and the Institute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, TX 78712, USA
    Development 130:4859-69. 2003
  8. pmc GL3 encodes a bHLH protein that regulates trichome development in arabidopsis through interaction with GL1 and TTG1
    C T Payne
    Molecular Cell and Developmental Biology and the Institute for Cellular and Molecular Biology, University of Texas, Austin, Texas 78712 1095, USA
    Genetics 156:1349-62. 2000
  9. pmc Allele-specific interactions between ttg and gl1 during trichome development in Arabidopsis thaliana
    J C Larkin
    Department of Biological Sciences, Louisiana State University, Baton Rouge, Louisiana 70803, USA
    Genetics 151:1591-604. 1999
  10. pmc The TRANSPARENT TESTA GLABRA1 locus, which regulates trichome differentiation and anthocyanin biosynthesis in Arabidopsis, encodes a WD40 repeat protein
    A R Walker
    Department of Plant Sciences, University of Cambridge, Downing Street, Cambridge CB2 3EA, United Kingdom
    Plant Cell 11:1337-50. 1999

Scientific Experts

  • J C Larkin
  • V Vaughan Symonds
  • A R Walker
  • Antonio Gonzalez
  • Mingzhe Zhao
  • Antoine Baudry
  • Rachappa Balkunde
  • Daniel Bouyer
  • Martin Hulskamp
  • Alan Lloyd
  • Hoai Nguyen Nguyen
  • Hongtao Zhao
  • Ying Gao
  • Lies Maes
  • Katja Wester
  • Michel Caboche
  • Victor Kirik
  • Loic Lepiniec
  • Fan Zhang
  • Jeffrey J Esch
  • Jun Hyeok Kim
  • Woo Young Hyun
  • Hojoung Lee
  • Suk Whan Hong
  • Ngoc Trinh Nguyen
  • Dandan Zhu
  • Ligeng Ma
  • Ying Cao
  • Xia Li
  • Xiaoxue Wang
  • Sujuan Cui
  • C T Payne
  • John Mendenhall
  • Yujia Huo
  • Dirk Inze
  • Christian Fleck
  • Kengo Morohashi
  • Martina Pesch
  • Yan Guo
  • Alain Goossens
  • Wanhong Cao
  • Xuechen Wang
  • Alan M Lloyd
  • Karen S Schumaker
  • John M Leavitt
  • Ximing Gong
  • Erich Grotewold
  • Friedrich Kragler
  • Arp Schnittger
  • Jens Timmer
  • Florian Geier
  • Liqin Fu
  • Jinfeng Zhao
  • Greg Hatlestad
  • Ullrich Herrmann
  • Myeong Min Lee
  • Zhengui Zheng
  • John Schiefelbein
  • David Oppenheimer
  • Bertrand Dubreucq
  • Bernd Weisshaar
  • Marc A Heim
  • A M Lloyd
  • C Thomas Payne
  • James Neizer
  • M David Marks
  • Brian Idelkope
  • Sampson Ndkium
  • Matthew Hillestad
  • Margaret Chen
  • Mark Sanders
  • F Zhang
  • M E Galway
  • R W Davis
  • J W Schiefelbein
  • J D Masucci
  • V Walbot

Detail Information

Publications19

  1. ncbi The TTG gene is required to specify epidermal cell fate and cell patterning in the Arabidopsis root
    M E Galway
    Department of Biology, University of Michigan, Ann Arbor 48109
    Dev Biol 166:740-54. 1994
    ..This normal positional relationship was absent in ttg (transparent testa glabrous) mutants (lacking trichomes, anthocyanins, and seed coat mucilage); epidermal cells in ..
  2. doi The TTG1-bHLH-MYB complex controls trichome cell fate and patterning through direct targeting of regulatory loci
    Mingzhe Zhao
    Section of Molecular Cell and Developmental Biology and The Institute for Cellular and Molecular Biology, The University of Texas at Austin, 2500 Speedway, Austin, TX 78712, USA
    Development 135:1991-9. 2008
    ..of proteins consisting of bHLH and MYB transcription factors, and a WD40 repeat protein, TRANSPARENT TESTA GLABRA1 (TTG1), act in concert to activate trichome initiation and patterning...
  3. ncbi TT8 controls its own expression in a feedback regulation involving TTG1 and homologous MYB and bHLH factors, allowing a strong and cell-specific accumulation of flavonoids in Arabidopsis thaliana
    Antoine Baudry
    Seed Biology Laboratory, UMR 204 INRA INAPG, Jean Pierre Bourgin Institute, Route de Saint Cyr, 78026 Versailles Cedex, France
    Plant J 46:768-79. 2006
    ..Moreover, the activity of this reporter construct was strongly affected in ttg1, TT2 overexpressers (OE), and PAP1-OE, suggesting interplay between TT2, PAP1, TTG1 and the activation of the TT8 ..
  4. pmc Functional specialization of the TRANSPARENT TESTA GLABRA1 network allows differential hormonal control of laminal and marginal trichome initiation in Arabidopsis rosette leaves
    Lies Maes
    Department of Plant Systems Biology, Flanders Institute for Biotechnology, Ghent University, 9052 Ghent, Belgium
    Plant Physiol 148:1453-64. 2008
    Trichome initiation in Arabidopsis (Arabidopsis thaliana) is controlled by the TRANSPARENT TESTA GLABRA1 (TTG1) network that consists of R2R3- and R1-type MYB-related transcription factors, basic helix-loop-helix (bHLH) proteins, and the ..
  5. ncbi Functional diversification of MYB23 and GL1 genes in trichome morphogenesis and initiation
    Victor Kirik
    Botanical Institute, University of Cologne, Gyrhofstrasse 15, 50931 Cologne, Germany
    Development 132:1477-85. 2005
    ....
  6. ncbi A contradictory GLABRA3 allele helps define gene interactions controlling trichome development in Arabidopsis
    Jeffrey J Esch
    Department of Plant Biology, University of Minnesota, St Paul, MN 55108 1095, USA
    Development 130:5885-94. 2003
    ..Yeast interaction assays comparing GL3 with gl3-sst proteins show that the mutant protein interaction with GL1 and TTG1 is decreased by 75% and 50%, respectively, but there is no difference in its interaction with TRY...
  7. ncbi A network of redundant bHLH proteins functions in all TTG1-dependent pathways of Arabidopsis
    Fan Zhang
    Molecular Cell and Developmental Biology, and the Institute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, TX 78712, USA
    Development 130:4859-69. 2003
    GLABRA3 (GL3) encodes a bHLH protein that interacts with the WD repeat protein, TTG1. GL3 overexpression suppresses the trichome defect of the pleiotropic ttg1 mutations...
  8. pmc GL3 encodes a bHLH protein that regulates trichome development in arabidopsis through interaction with GL1 and TTG1
    C T Payne
    Molecular Cell and Developmental Biology and the Institute for Cellular and Molecular Biology, University of Texas, Austin, Texas 78712 1095, USA
    Genetics 156:1349-62. 2000
    ..Mutations in TRANSPARENT TESTA GLABRA1 (TTG1) result in several pleiotropic defects including an almost complete lack of trichomes...
  9. pmc Allele-specific interactions between ttg and gl1 during trichome development in Arabidopsis thaliana
    J C Larkin
    Department of Biological Sciences, Louisiana State University, Baton Rouge, Louisiana 70803, USA
    Genetics 151:1591-604. 1999
    ..Two genes that play an essential role in the initiation of trichome development are GL1 and TTG. Mutations in either gene prevent the initiation of most trichomes...
  10. pmc The TRANSPARENT TESTA GLABRA1 locus, which regulates trichome differentiation and anthocyanin biosynthesis in Arabidopsis, encodes a WD40 repeat protein
    A R Walker
    Department of Plant Sciences, University of Cambridge, Downing Street, Cambridge CB2 3EA, United Kingdom
    Plant Cell 11:1337-50. 1999
    The TRANSPARENT TESTA GLABRA1 (TTG1) locus regulates several developmental and biochemical pathways in Arabidopsis, including the formation of hairs on leaves, stems, and roots, and the production of seed mucilage and anthocyanin pigments...
  11. pmc A single amino acid substitution in IIIf subfamily of basic helix-loop-helix transcription factor AtMYC1 leads to trichome and root hair patterning defects by abolishing its interaction with partner proteins in Arabidopsis
    Hongtao Zhao
    Hebei Key Laboratory of Molecular Cell Biology, College of Biological Sciences, Hebei Normal University, Shijiazhuang 050016 Hebei, China
    J Biol Chem 287:14109-21. 2012
    ..requires a combination of three groups of proteins, including the WD40 repeat protein transparent TESTA GLABRA1 (TTG1), R2R3 repeat MYB protein GLABRA1 (GL1), or werewolf (WER) and the IIIf subfamily of basic helix-loop-helix (bHLH) ..
  12. doi TTG1-mediated flavonols biosynthesis alleviates root growth inhibition in response to ABA
    Hoai Nguyen Nguyen
    College of Life Sciences and Biotechnology, Korea University, 1, 5 ka Anam dong, Seongbuk gu, Seoul, 136 713, Republic of Korea
    Plant Cell Rep 32:503-14. 2013
    ..The recessive TRANSPARENT TESTA GLABRA 1 (ttg1) mutant was characterized on ABA and sucrose treatments...
  13. ncbi TT2, TT8, and TTG1 synergistically specify the expression of BANYULS and proanthocyanidin biosynthesis in Arabidopsis thaliana
    Antoine Baudry
    Seed Biology Laboratory, UMR 204 INRA INAPG, Jean Pierre Bourgin Institute, Route de Saint Cyr, 78026 Versailles Cedex, France
    Plant J 39:366-80. 2004
    Genetic analyses have demonstrated that together with TTG1, a WD-repeat (WDR) protein, TT2 (MYB), and TT8 (bHLH) are necessary for the correct expression of BANYULS (BAN)...
  14. pmc Two-dimensional patterning by a trapping/depletion mechanism: the role of TTG1 and GL3 in Arabidopsis trichome formation
    Daniel Bouyer
    Botanical Institute III, University of Cologne, Koln, Germany, 2 Department of Biology, University of Freiburg, Freiburg, Germany
    PLoS Biol 6:e141. 2008
    ..involved by which patterning is governed by the removal of the trichome-promoting factor TRANSPARENT TESTA GLABRA1 (TTG1) from non-trichome cells...
  15. doi SAD2 in Arabidopsis functions in trichome initiation through mediating GL3 function and regulating GL1, TTG1 and GL2 expression
    Ying Gao
    State Key Laboratory of Plant Physiology and Biochemistry, College of Biological Sciences, China Agricultural University, Beijing 100094, China
    J Integr Plant Biol 50:906-17. 2008
    ..transcriptional networks and include GLABROUS1 (GL1), GLABRA2 (GL2), GLABRA3 (GL3) and TRANSPARENT TESTA GLABRA1 (TTG1)...
  16. doi TTG1 complex MYBs, MYB5 and TT2, control outer seed coat differentiation
    Antonio Gonzalez
    Section of Molecular Cell and Developmental Biology and The Institute for Cellular and Molecular Biology, The University of Texas at Austin, 2500 Speedway, Austin, TX 78712, USA
    Dev Biol 325:412-21. 2009
    ..Although the TTG1-dependent R2R3 MYBs are considered to be highly pathway specific, identification of MYBs responsible for outer seed ..
  17. pmc Natural allelic variation defines a role for ATMYC1: trichome cell fate determination
    V Vaughan Symonds
    Institute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, Texas, United States of America
    PLoS Genet 7:e1002069. 2011
    ..thaliana and indicate that the transcription factors that make up the TTG1 genetic pathway generally may be important sources of epidermal variation in plants.
  18. doi Nuclear trapping by GL3 controls intercellular transport and redistribution of TTG1 protein in Arabidopsis
    Rachappa Balkunde
    University of Cologne, Botanical Institute III, Z├╝lpicher Strasse 47b, 50674 Koln, Germany
    Development 138:5039-48. 2011
    ..operate during this process such that GLABRA3 (GL3) traps the trichome-promoting factor TRANSPARENT TESTA GLABRA1 (TTG1) in trichomes that, in turn, results in a depletion of TTG1 in trichome neighbouring cells...
  19. ncbi Regulation of the anthocyanin biosynthetic pathway by the TTG1/bHLH/Myb transcriptional complex in Arabidopsis seedlings
    Antonio Gonzalez
    Molecular Cell and Developmental Biology, and Institute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, TX 78 712, USA
    Plant J 53:814-27. 2008
    ..Myb regulators remain to be conclusively identified, and little is known about anthocyanin pathway regulation by TTG1-dependent transcriptional complexes...