Gene Symbol: TOPP4
Description: type one serine/threonine protein phosphatase 4
Alias: type one serine/threonine protein phosphatase 4, type one serine/threonine protein phosphatase 4
Species: thale cress

Top Publications

  1. Takemiya A, Ariyoshi C, Shimazaki K. Identification and functional characterization of inhibitor-3, a regulatory subunit of protein phosphatase 1 in plants. Plant Physiol. 2009;150:144-56 pubmed publisher
    ..These results define Inh3 as a regulatory subunit of PP1 in plants and suggest that Inh3 plays a crucial role in early embryogenesis in Arabidopsis...
  2. Templeton G, Nimick M, Morrice N, Campbell D, Goudreault M, Gingras A, et al. Identification and characterization of AtI-2, an Arabidopsis homologue of an ancient protein phosphatase 1 (PP1) regulatory subunit. Biochem J. 2011;435:73-83 pubmed publisher
    ..TAP (tandem affinity purification)-tag experiments with plant I-2 showed in vivo association with several Arabidopsis PP1 isoforms and identified other potential I-2 binding proteins. ..
  3. Takemiya A, Yamauchi S, Yano T, Ariyoshi C, Shimazaki K. Identification of a regulatory subunit of protein phosphatase 1 which mediates blue light signaling for stomatal opening. Plant Cell Physiol. 2013;54:24-35 pubmed publisher
    ..PRSL1 did not affect the catalytic activity of Arabidopsis PP1c but it stimulated the localization of PP1c in the cytoplasm. We conclude that PRSL1 functions as a regulatory subunit of PP1 and regulates blue light signaling in stomata. ..
  4. Qin Q, Wang W, Guo X, Yue J, Huang Y, Xu X, et al. Arabidopsis DELLA protein degradation is controlled by a type-one protein phosphatase, TOPP4. PLoS Genet. 2014;10:e1004464 pubmed publisher
    ..We have identified a dwarfed dominant-negative Arabidopsis mutant, named topp4-1. Reduced expression of TOPP4 using an artificial microRNA strategy also resulted in a dwarfed phenotype...
  5. Yue J, Qin Q, Meng S, Jing H, Gou X, Li J, et al. TOPP4 Regulates the Stability of PHYTOCHROME INTERACTING FACTOR5 during Photomorphogenesis in Arabidopsis. Plant Physiol. 2016;170:1381-97 pubmed publisher
    ..In this study, we identified a type 1 protein phosphatase, TOPP4, that is essential for PIF5 protein stability in Arabidopsis (Arabidopsis thaliana)...
  6. Smith R, Walker J. Expression of multiple type 1 phosphoprotein phosphatases in Arabidopsis thaliana. Plant Mol Biol. 1993;21:307-16 pubmed
    ..In this study, we report the isolation of five distinct Arabidopsis cDNA clones (TOPP1, TOPP2, TOPP3, TOPP4 and TOPP5) which encode the catalytic subunit (PP1c) of type 1 protein phosphatases...
  7. Guo X, Qin Q, Yan J, Niu Y, Huang B, Guan L, et al. TYPE-ONE PROTEIN PHOSPHATASE4 regulates pavement cell interdigitation by modulating PIN-FORMED1 polarity and trafficking in Arabidopsis. Plant Physiol. 2015;167:1058-75 pubmed publisher
    ..Here, we show that a type-one protein phosphatase, TOPP4, is essential for the formation of interdigitated pavement cell (PC) pattern in Arabidopsis (Arabidopsis thaliana) ..