TGA3

Summary

Gene Symbol: TGA3
Description: transcription factor TGA3
Alias: F2E2.14, F2E2_14, TGA1A-related gene 3, TRANSCRIPTION FACTOR TGA3, transcription factor TGA3
Species: thale cress

Top Publications

  1. Liu G, Holub E, Alonso J, Ecker J, Fobert P. An Arabidopsis NPR1-like gene, NPR4, is required for disease resistance. Plant J. 2005;41:304-18 pubmed
    ..These results indicate that NPR4 is required for basal defense against pathogens, and that it may be implicated in the cross-talk between the SA- and JA-dependent signaling pathways. ..
  2. Deppmann C, Alvania R, Taparowsky E. Cross-species annotation of basic leucine zipper factor interactions: Insight into the evolution of closed interaction networks. Mol Biol Evol. 2006;23:1480-92 pubmed
    ..Finally, we discuss the fundamental similarities and differences between dimerization networks within the context of bZIP factor evolution. ..
  3. Choi J, Huh S, Kojima M, Sakakibara H, Paek K, Hwang I. The cytokinin-activated transcription factor ARR2 promotes plant immunity via TGA3/NPR1-dependent salicylic acid signaling in Arabidopsis. Dev Cell. 2010;19:284-95 pubmed publisher
    ..The salicylic acid (SA) response factor TGA3 binds ARR2, and mutation of TGA-binding cis-elements in the Pr1 promoter abolished cytokinin- and ARR2-dependent ..
  4. Li S, Gutsche N, Zachgo S. The ROXY1 C-terminal L**LL motif is essential for the interaction with TGA transcription factors. Plant Physiol. 2011;157:2056-68 pubmed publisher
    ..Furthermore, two separate TGA domains were identified by deletion experiments as being essential for mediating TGA protein interactions with ROXYs. ..
  5. Szymanski D, Liao B, Zielinski R. Calmodulin isoforms differentially enhance the binding of cauliflower nuclear proteins and recombinant TGA3 to a region derived from the Arabidopsis Cam-3 promoter. Plant Cell. 1996;8:1069-77 pubmed
    ..CaM also binds recombinant TGA3 and enhances its binding to the same Cam-3 promoter element...
  6. Kesarwani M, Yoo J, Dong X. Genetic interactions of TGA transcription factors in the regulation of pathogenesis-related genes and disease resistance in Arabidopsis. Plant Physiol. 2007;144:336-46 pubmed
    ..In this study, we characterized six TGA factors by reverse genetics. We show that TGA3 is required for both basal and 2,6-dichloroisonicotinic acid-induced transcription of PR genes...
  7. Li S, Lauri A, Ziemann M, Busch A, Bhave M, Zachgo S. Nuclear activity of ROXY1, a glutaredoxin interacting with TGA factors, is required for petal development in Arabidopsis thaliana. Plant Cell. 2009;21:429-41 pubmed publisher
    ..Additionally, ROXY1 affects later petal morphogenesis, probably by modulating other TGA factors that might act redundantly during differentiation of second whorl organs. ..
  8. Zhang Y, Cheng Y, Qu N, Zhao Q, Bi D, Li X. Negative regulation of defense responses in Arabidopsis by two NPR1 paralogs. Plant J. 2006;48:647-56 pubmed
    ..NPR3 and NPR4 interact with TGA2, TGA3, TGA5 and TGA6 in yeast two-hybrid assays...
  9. Zhou J, Trifa Y, Silva H, Pontier D, Lam E, Shah J, et al. NPR1 differentially interacts with members of the TGA/OBF family of transcription factors that bind an element of the PR-1 gene required for induction by salicylic acid. Mol Plant Microbe Interact. 2000;13:191-202 pubmed
    ..Six TGA family members were tested and shown to differentially interact with NPR1: TGA2 and TGA3 showed strong affinity for NPR1; TGA5 and TGA6 exhibited weaker affinity; and TGA1 and TGA4 displayed little or no ..
  10. Despres C, Delong C, Glaze S, Liu E, Fobert P. The Arabidopsis NPR1/NIM1 protein enhances the DNA binding activity of a subgroup of the TGA family of bZIP transcription factors. Plant Cell. 2000;12:279-90 pubmed
    ..Coupled with observations that the DNA binding activity of TGA factors is deregulated in npr1 plants, the results suggest that NPR1-mediated DNA binding of TGA2 is critical for activation of defense genes. ..

Detail Information

Publications12

  1. Liu G, Holub E, Alonso J, Ecker J, Fobert P. An Arabidopsis NPR1-like gene, NPR4, is required for disease resistance. Plant J. 2005;41:304-18 pubmed
    ..These results indicate that NPR4 is required for basal defense against pathogens, and that it may be implicated in the cross-talk between the SA- and JA-dependent signaling pathways. ..
  2. Deppmann C, Alvania R, Taparowsky E. Cross-species annotation of basic leucine zipper factor interactions: Insight into the evolution of closed interaction networks. Mol Biol Evol. 2006;23:1480-92 pubmed
    ..Finally, we discuss the fundamental similarities and differences between dimerization networks within the context of bZIP factor evolution. ..
  3. Choi J, Huh S, Kojima M, Sakakibara H, Paek K, Hwang I. The cytokinin-activated transcription factor ARR2 promotes plant immunity via TGA3/NPR1-dependent salicylic acid signaling in Arabidopsis. Dev Cell. 2010;19:284-95 pubmed publisher
    ..The salicylic acid (SA) response factor TGA3 binds ARR2, and mutation of TGA-binding cis-elements in the Pr1 promoter abolished cytokinin- and ARR2-dependent ..
  4. Li S, Gutsche N, Zachgo S. The ROXY1 C-terminal L**LL motif is essential for the interaction with TGA transcription factors. Plant Physiol. 2011;157:2056-68 pubmed publisher
    ..Furthermore, two separate TGA domains were identified by deletion experiments as being essential for mediating TGA protein interactions with ROXYs. ..
  5. Szymanski D, Liao B, Zielinski R. Calmodulin isoforms differentially enhance the binding of cauliflower nuclear proteins and recombinant TGA3 to a region derived from the Arabidopsis Cam-3 promoter. Plant Cell. 1996;8:1069-77 pubmed
    ..CaM also binds recombinant TGA3 and enhances its binding to the same Cam-3 promoter element...
  6. Kesarwani M, Yoo J, Dong X. Genetic interactions of TGA transcription factors in the regulation of pathogenesis-related genes and disease resistance in Arabidopsis. Plant Physiol. 2007;144:336-46 pubmed
    ..In this study, we characterized six TGA factors by reverse genetics. We show that TGA3 is required for both basal and 2,6-dichloroisonicotinic acid-induced transcription of PR genes...
  7. Li S, Lauri A, Ziemann M, Busch A, Bhave M, Zachgo S. Nuclear activity of ROXY1, a glutaredoxin interacting with TGA factors, is required for petal development in Arabidopsis thaliana. Plant Cell. 2009;21:429-41 pubmed publisher
    ..Additionally, ROXY1 affects later petal morphogenesis, probably by modulating other TGA factors that might act redundantly during differentiation of second whorl organs. ..
  8. Zhang Y, Cheng Y, Qu N, Zhao Q, Bi D, Li X. Negative regulation of defense responses in Arabidopsis by two NPR1 paralogs. Plant J. 2006;48:647-56 pubmed
    ..NPR3 and NPR4 interact with TGA2, TGA3, TGA5 and TGA6 in yeast two-hybrid assays...
  9. Zhou J, Trifa Y, Silva H, Pontier D, Lam E, Shah J, et al. NPR1 differentially interacts with members of the TGA/OBF family of transcription factors that bind an element of the PR-1 gene required for induction by salicylic acid. Mol Plant Microbe Interact. 2000;13:191-202 pubmed
    ..Six TGA family members were tested and shown to differentially interact with NPR1: TGA2 and TGA3 showed strong affinity for NPR1; TGA5 and TGA6 exhibited weaker affinity; and TGA1 and TGA4 displayed little or no ..
  10. Despres C, Delong C, Glaze S, Liu E, Fobert P. The Arabidopsis NPR1/NIM1 protein enhances the DNA binding activity of a subgroup of the TGA family of bZIP transcription factors. Plant Cell. 2000;12:279-90 pubmed
    ..Coupled with observations that the DNA binding activity of TGA factors is deregulated in npr1 plants, the results suggest that NPR1-mediated DNA binding of TGA2 is critical for activation of defense genes. ..
  11. Hepworth S, Zhang Y, McKim S, Li X, Haughn G. BLADE-ON-PETIOLE-dependent signaling controls leaf and floral patterning in Arabidopsis. Plant Cell. 2005;17:1434-48 pubmed
  12. Miao Z, Liu X, Lam E. TGA3 is a distinct member of the TGA family of bZIP transcription factors in Arabidopsis thaliana. Plant Mol Biol. 1994;25:1-11 pubmed
    ..to find a model plant system that may have less genomic complexity, we have now characterized a TGA1a-related gene (TGA3) from Arabidopsis thaliana...