TED4

Summary

Gene Symbol: TED4
Description: Plant heme oxygenase (decyclizing) family protein
Alias: ARABIDOPSIS THALIANA HEME OXYGENASE 1, ATHO1, F18A8.4, F18A8_4, GENOMES UNCOUPLED 2, GUN2, HEME OXYGENASE, HEME OXYGENASE 1, HEME OXYGENASE 6, HO1, HY1, HY6, PLASTID HEME OXYGENASE, REVERSAL OF THE DET PHENOTYPE 4, Plant heme oxygenase (decyclizing) family protein
Species: thale cress

Top Publications

  1. Muramoto T, Kohchi T, Yokota A, Hwang I, Goodman H. The Arabidopsis photomorphogenic mutant hy1 is deficient in phytochrome chromophore biosynthesis as a result of a mutation in a plastid heme oxygenase. Plant Cell. 1999;11:335-48 pubmed
    ..These results indicate that the Arabidopsis HY1 gene encodes a plastid heme oxygenase necessary for phytochrome chromophore biosynthesis.
  2. Emborg T, Walker J, Noh B, Vierstra R. Multiple heme oxygenase family members contribute to the biosynthesis of the phytochrome chromophore in Arabidopsis. Plant Physiol. 2006;140:856-68 pubmed
    ..Arabidopsis (Arabidopsis thaliana) contains four possible HO genes (HY1, HO2-4)...
  3. Gisk B, Yasui Y, Kohchi T, Frankenberg Dinkel N. Characterization of the haem oxygenase protein family in Arabidopsis thaliana reveals a diversity of functions. Biochem J. 2010;425:425-34 pubmed publisher
    ..Arabidopsis thaliana contains one major biochemically characterized HO (HY1) and three additional putative HOs (HO2, HO3 and HO4)...
  4. Xie Y, Xu D, Cui W, Shen W. Mutation of Arabidopsis HY1 causes UV-C hypersensitivity by impairing carotenoid and flavonoid biosynthesis and the down-regulation of antioxidant defence. J Exp Bot. 2012;63:3869-83 pubmed publisher
    ..In this study, the link between Arabidopsis thaliana HO-1 (HY1) and UV-C tolerance was investigated at the genetic and molecular levels...
  5. Xie Y, Xu S, Han B, Wu M, Yuan X, Han Y, et al. Evidence of Arabidopsis salt acclimation induced by up-regulation of HY1 and the regulatory role of RbohD-derived reactive oxygen species synthesis. Plant J. 2011;66:280-92 pubmed publisher
    In Arabidopsis thaliana, a family of four genes (HY1, HO2, HO3 and HO4) encode haem oxygenase (HO), and play a major role in phytochrome chromophore biosynthesis...
  6. Lee H, Mochizuki N, Masuda T, Buckhout T. Disrupting the bimolecular binding of the haem-binding protein 5 (AtHBP5) to haem oxygenase 1 (HY1) leads to oxidative stress in Arabidopsis. J Exp Bot. 2012;63:5967-78 pubmed publisher
    ..In this report, it is shown that AtHBP5 binds haem and interacts with the haem oxygenase, HY1, in both yeast two-hybrid and BiFC assays...
  7. Li H, Song J, Zhao W, Yang Z. AtHO1 is involved in iron homeostasis in an NO-dependent manner. Plant Cell Physiol. 2013;54:1105-17 pubmed publisher
    AtHO1 (HY1) encodes heme oxygenase-1 in Arabidopsis, catalyzing cleavage of heme to biliverdin with the release of iron and carbon monoxide (CO)...
  8. Xie Y, Mao Y, Lai D, Zhang W, Zheng T, Shen W. Roles of NIA/NR/NOA1-dependent nitric oxide production and HY1 expression in the modulation of Arabidopsis salt tolerance. J Exp Bot. 2013;64:3045-60 pubmed publisher
    ..roles of Arabidopsis nitric oxide-associated 1 (NOA1)-associated nitric oxide (NO) production and haem oxygenase 1 (HY1) expression in salt tolerance, their integrative signalling pathway remains largely unknown...
  9. Xie Y, Mao Y, Duan X, Zhou H, Lai D, Zhang Y, et al. Arabidopsis HY1-Modulated Stomatal Movement: An Integrative Hub Is Functionally Associated with ABI4 in Dehydration-Induced ABA Responsiveness. Plant Physiol. 2016;170:1699-713 pubmed publisher
    b>Heme oxygenase (HO; EC 1.14.99.3) has recently been proposed as a novel component in mediating wide ranges of the plant adaptive signaling processes...

More Information

Publications13

  1. Susek R, Ausubel F, Chory J. Signal transduction mutants of Arabidopsis uncouple nuclear CAB and RBCS gene expression from chloroplast development. Cell. 1993;74:787-99 pubmed
    ..We have identified at least three Arabidopsis nuclear genes (GUN1, GUN2, and GUN3) necessary for coupling the expression of some nuclear genes to the functional state of the chloroplast...
  2. Lopez Juez E, Dillon E, Magyar Z, Khan S, Hazeldine S, de Jager S, et al. Distinct light-initiated gene expression and cell cycle programs in the shoot apex and cotyledons of Arabidopsis. Plant Cell. 2008;20:947-68 pubmed publisher
    ..These data provide the basis for reconstruction of the regulatory networks for light-regulated meristem, leaf, and cotyledon development. ..
  3. Prasad B, Kumar S, Nandi A, Chattopadhyay S. Functional interconnections of HY1 with MYC2 and HY5 in Arabidopsis seedling development. BMC Plant Biol. 2012;12:37 pubmed publisher
    ..Arabidopsis HY1/HO1 is a rate-limiting enzyme involved in biosynthesis of phytochrome chromophore...
  4. Han B, Yang Z, Xie Y, Nie L, Cui J, Shen W. Arabidopsis HY1 confers cadmium tolerance by decreasing nitric oxide production and improving iron homeostasis. Mol Plant. 2014;7:388-403 pubmed publisher
    Up-regulation of the gene that encodes intracellular heme oxygenase 1 (HO1) benefits plants under cadmium (Cd(2+)) stress; however, the molecular mechanisms remain unclear...