Gene Symbol: TCP1
Description: TCP family transcription factor
Alias: F1N21.8, TCP family transcription factor
Species: thale cress

Top Publications

  1. Guo Z, Fujioka S, Blancaflor E, Miao S, Gou X, Li J. TCP1 modulates brassinosteroid biosynthesis by regulating the expression of the key biosynthetic gene DWARF4 in Arabidopsis thaliana. Plant Cell. 2010;22:1161-73 pubmed publisher
    Brassinosteroids (BRs) are essential phytohormones regulating normal plant growth and development. TCP1, a gene thought to be involved in floral organ symmetric control, was identified as a genetic suppressor of a weak BR receptor mutant, ..
  2. Yang X, Pang H, Liu B, Qiu Z, Gao Q, Wei L, et al. Evolution of double positive autoregulatory feedback loops in CYCLOIDEA2 clade genes is associated with the origin of floral zygomorphy. Plant Cell. 2012;24:1834-47 pubmed publisher
  3. Chen G, Sun J, Liu M, Liu J, Yang W. SPOROCYTELESS is a novel embryophyte-specific transcription repressor that interacts with TPL and TCP proteins in Arabidopsis. J Genet Genomics. 2014;41:617-25 pubmed publisher
    ..Together, we propose that SPL and SPEARs most likely belong to a novel transcription repressor family in land plants which may play a variety of developmental roles in plants. ..
  4. Cubas P, Lauter N, Doebley J, Coen E. The TCP domain: a motif found in proteins regulating plant growth and development. Plant J. 1999;18:215-22 pubmed
    ..Some of these genes may have been recruited during plant evolution to generate new morphological traits. ..
  5. Cubas P, Coen E, Zapater J. Ancient asymmetries in the evolution of flowers. Curr Biol. 2001;11:1050-2 pubmed
  6. Citerne H, Luo D, Pennington R, Coen E, Cronk Q. A phylogenomic investigation of CYCLOIDEA-like TCP genes in the Leguminosae. Plant Physiol. 2003;131:1042-53 pubmed
    Numerous TCP genes (transcription factors with a TCP domain) occur in legumes. Genes of this class in Arabidopsis (TCP1) and snapdragon (Antirrhinum majus; CYCLOIDEA) have been shown to be asymmetrically expressed in developing floral ..
  7. Beyhl D, Hortensteiner S, Martinoia E, Farmer E, Fromm J, Marten I, et al. The fou2 mutation in the major vacuolar cation channel TPC1 confers tolerance to inhibitory luminal calcium. Plant J. 2009;58:715-23 pubmed publisher
    ..In response to wounding fou2 plants might thus elicit strong vacuole-derived cytosolic Ca2+ signals resulting in overproduction of jasmonate. ..
  8. Koyama T, Sato F, Ohme Takagi M. A role of TCP1 in the longitudinal elongation of leaves in Arabidopsis. Biosci Biotechnol Biochem. 2010;74:2145-7 pubmed
    We clarified important roles of Arabidopsis TCP1, a member of the TEOSINTE BRANCHED1, CYCLOIDEA, and PCF (TCP) transcription factors, in the longitudinal elongation of petioles, rosette leaves and inflorescent stems...
  9. An J, Guo Z, Gou X, Li J. TCP1 positively regulates the expression of DWF4 in Arabidopsis thaliana. Plant Signal Behav. 2011;6:1117-8 pubmed publisher
    ..The detailed molecular mechanisms controlling bioactive levels of BRs, however, are not fully understood. TCP1 is a member of class II TCP proteins in Arabidopsis thaliana...

More Information


  1. Ballester P, Navarrete Gómez M, Carbonero P, Oñate Sánchez L, Ferrándiz C. Leaf expansion in Arabidopsis is controlled by a TCP-NGA regulatory module likely conserved in distantly related species. Physiol Plant. 2015;155:21-32 pubmed publisher
    ..Moreover, we have found that this TCP-NGA regulatory interaction is likely conserved in angiosperms, including important crop species, for which the regulation of leaf development is a target for biotechnological improvement. ..
  2. Gao Y, Zhang D, Li J. TCP1 Modulates DWF4 Expression via Directly Interacting with the GGNCCC Motifs in the Promoter Region of DWF4 in Arabidopsis thaliana. J Genet Genomics. 2015;42:383-92 pubmed publisher
    Our previous studies indicated that TCP1 is a positive regulator of the brassinosteroid (BR) biosynthesis pathway by mediating the transcription of DWF4, one of the key BR biosynthetic genes in Arabidopsis thaliana...