SRFR1

Summary

Gene Symbol: SRFR1
Description: Tetratricopeptide repeat (TPR)-like superfamily protein
Alias: F6G17.110, F6G17_110, SUPPRESSOR OF RPS4-RLD 1, Tetratricopeptide repeat (TPR)-like superfamily protein
Species: thale cress

Top Publications

  1. Kwon S, Koczan J, Gassmann W. Two Arabidopsis srfr (suppressor of rps4-RLD) mutants exhibit avrRps4-specific disease resistance independent of RPS4. Plant J. 2004;40:366-75 pubmed
    ..In this report, we describe two non-allelic srfr (suppressor of rps4-RLD) mutants, srfr1 and srfr3, that were susceptible to virulent P. syringae pv...
  2. Kwon S, Kim S, Bhattacharjee S, Noh J, Gassmann W. SRFR1, a suppressor of effector-triggered immunity, encodes a conserved tetratricopeptide repeat protein with similarity to transcriptional repressors. Plant J. 2009;57:109-19 pubmed publisher
    ..Previously, we identified Arabidopsis suppressor of rps4-RLD 1 (srfr1) mutants with enhanced resistance to the bacterial effector AvrRps4...
  3. Kim S, Kwon S, Saha D, Anyanwu N, Gassmann W. Resistance to the Pseudomonas syringae effector HopA1 is governed by the TIR-NBS-LRR protein RPS6 and is enhanced by mutations in SRFR1. Plant Physiol. 2009;150:1723-32 pubmed publisher
    ..We previously characterized SRFR1 as a negative regulator of avrRps4-triggered immunity...
  4. Li Y, Li S, Bi D, Cheng Y, Li X, Zhang Y. SRFR1 negatively regulates plant NB-LRR resistance protein accumulation to prevent autoimmunity. PLoS Pathog. 2010;6:e1001111 pubmed publisher
    ..revealed that one of the mutant genes encodes a conserved TPR domain-containing protein previously known as SRFR1 (SUPPRESSOR OF rps4-RLD)...
  5. Kim S, Gao F, Bhattacharjee S, Adiasor J, Nam J, Gassmann W. The Arabidopsis resistance-like gene SNC1 is activated by mutations in SRFR1 and contributes to resistance to the bacterial effector AvrRps4. PLoS Pathog. 2010;6:e1001172 pubmed publisher
    The SUPPRESSOR OF rps4-RLD1 (SRFR1) gene was identified based on enhanced AvrRps4-triggered resistance in the naturally susceptible Arabidopsis accession RLD...
  6. Nguyen P, Pike S, Wang J, Nepal Poudel A, Heinz R, Schultz J, et al. The Arabidopsis immune regulator SRFR1 dampens defences against herbivory by Spodoptera exigua and parasitism by Heterodera schachtii. Mol Plant Pathol. 2016;17:588-600 pubmed publisher
    ..Previously, we identified SUPPRESSOR OF rps4-RLD1 (SRFR1) as a negative regulator of ENHANCED DISEASE SUSCEPTIBILITY1 (EDS1)-dependent effector-triggered immunity against ..
  7. Bhattacharjee S, Halane M, Kim S, Gassmann W. Pathogen effectors target Arabidopsis EDS1 and alter its interactions with immune regulators. Science. 2011;334:1405-8 pubmed publisher
    ..complexes with the TIR-NB-LRR disease resistance proteins RPS4 and RPS6 and with the negative immune regulator SRFR1 at a cytoplasmic membrane. Further, the cognate bacterial effectors AvrRps4 and HopA1 disrupt these EDS1 complexes...
  8. Kim S, Son G, Bhattacharjee S, Kim H, Nam J, Nguyen P, et al. The Arabidopsis immune adaptor SRFR1 interacts with TCP transcription factors that redundantly contribute to effector-triggered immunity. Plant J. 2014;78:978-89 pubmed publisher
    ..We previously identified SUPPRESSOR OF rps4-RLD1 (SRFR1) as a negative regulator specifically of effector-triggered immunity...