Gene Symbol: SQN
Description: peptidyl-prolyl cis-trans isomerase / cyclophilin-40 (CYP40) / rotamase
Alias: CYCLOPHILIN 40, CYCLOPHILIN-40, CYP40, F19G14.21, F19G14_21, SQUINT, peptidyl-prolyl cis-trans isomerase / cyclophilin-40 (CYP40) / rotamase
Species: thale cress
Berardini T, Bollman K, Sun H, Poethig R. Regulation of vegetative phase change in Arabidopsis thaliana by cyclophilin 40. Science. 2001;291:2405-7 pubmed
..SQN encodes the Arabidopsis homolog of cyclophilin 40 (CyP40), a protein found in association with the Hsp90 chaperone complex in yeast, mammals, and plants...
Prunet N, Morel P, Thierry A, Eshed Y, Bowman J, Negrutiu I, et al
. REBELOTE, SQUINT, and ULTRAPETALA1 function redundantly in the temporal regulation of floral meristem termination in Arabidopsis thaliana. Plant Cell. 2008;20:901-19 pubmed publisher
..Here, we report on three independent genes, a novel gene REBELOTE (RBL; protein of unknown function), SQUINT (SQN; a cyclophilin), and ULTRAPETALA1 (ULT1; a putative transcription factor) that redundantly influence floral ..
Tucker M, Roodbarkelari F, Truernit E, Adamski N, Hinze A, Lohmüller B, et al
. Accession-specific modifiers act with ZWILLE/ARGONAUTE10 to maintain shoot meristem stem cells during embryogenesis in Arabidopsis. BMC Genomics. 2013;14:809 pubmed publisher
..profiles to QTL map data revealed candidate FHE genes, including the Arabidopsis Cyclophilin-40 homologue SQUINT (SQN), and functional studies revealed a previously uncharacterised role for SQN in stem cell regulation...
Prunet N, Morel P, Champelovier P, Thierry A, Negrutiu I, Jack T, et al
. SQUINT promotes stem cell homeostasis and floral meristem termination in Arabidopsis through APETALA2 and CLAVATA signalling. J Exp Bot. 2015;66:6905-16 pubmed publisher
..Here, an analysis of the role of SQUINT (SQN) in stem cell dynamics in Arabidopsis is reported...
Song H, Fan P, Shi W, Zhao R, Li Y. Expression of five AtHsp90 genes in Saccharomyces cerevisiae reveals functional differences of AtHsp90s under abiotic stresses. J Plant Physiol. 2010;167:1172-8 pubmed publisher
..either pre-protein or mature forms of organellar AtHsp90s could interact with cofactors cpHsp70, Hsp70, Hsp70t-2, Cyp40, p23 and a substrate protein of NOS, while cytosolic AtHsp90s could not interact with them...
Earley K, Poethig R. Binding of the cyclophilin 40 ortholog SQUINT to Hsp90 protein is required for SQUINT function in Arabidopsis. J Biol Chem. 2011;286:38184-9 pubmed publisher
SQN (SQUINT) is the Arabidopsis ortholog of the immunophilin CyP40 (cyclophilin 40) and promotes microRNA activity by promoting the activity of AGO1...