Gene Symbol: SK 11
Description: shaggy-related kinase 11
Alias: ARABIDOPSIS THALIANA SHAGGY-RELATED KINASE 11, ASKALPHA, ASKalpha, ATSK11, Arabidopsis GSK alpha, F2P16.21, F2P16_21, shaggy-related kinase 11, shaggy-related kinase 11
Species: thale cress
Bianchi M, Guivarc h D, Thomas M, Woodgett J, Kreis M. Arabidopsis homologs of the shaggy and GSK-3 protein kinases: molecular cloning and functional expression in Escherichia coli. Mol Gen Genet. 1994;242:337-45 pubmed
..The high conservation of the protein kinases of GSK-3 family, and their action at the transcriptional level, suggest that the ASK proteins have important functions in higher plants. ..
Dornelas M, Lejeune B, Dron M, Kreis M. The Arabidopsis SHAGGY-related protein kinase (ASK) gene family: structure, organization and evolution. Gene. 1998;212:249-57 pubmed
..Eight out of the ten predicted ASK genes were mapped and shown to be dispersed over the five Arabidopsis chromosomes. A tentative model for the organization and evolution of the Arabidopsis ASK genes is presented...
Zhang W, Ito H, Quint M, Huang H, Noël L, Gray W. Genetic analysis of CAND1-CUL1 interactions in Arabidopsis supports a role for CAND1-mediated cycling of the SCFTIR1 complex. Proc Natl Acad Sci U S A. 2008;105:8470-5 pubmed publisher
..The fact that both decreased and increased CAND1-CUL1 interactions result in reduced SCF(TIR1) activity in vivo strongly supports the hypothesis that CAND1-mediated cycling is required for optimal SCF function. ..
Dal Santo S, Stampfl H, Krasensky J, Kempa S, Gibon Y, Petutschnig E, et al
. Stress-induced GSK3 regulates the redox stress response by phosphorylating glucose-6-phosphate dehydrogenase in Arabidopsis. Plant Cell. 2012;24:3380-92 pubmed
..Our results reveal a novel mechanism of G6PD adaptive regulation that is critical for the cellular stress response. ..
Zhu J, Li Y, Cao D, Yang H, Oh E, Bi Y, et al
. The F-box Protein KIB1 Mediates Brassinosteroid-Induced Inactivation and Degradation of GSK3-like Kinases in Arabidopsis. Mol Cell. 2017;66:648-657.e4 pubmed publisher
..Our study demonstrates that KIB1 plays an essential role in BR signaling by inhibiting BIN2 through dual mechanisms of blocking substrate access and promoting degradation. ..
Dornelas M, van Lammeren A, Kreis M. Arabidopsis thaliana SHAGGY-related protein kinases (AtSK11 and 12) function in perianth and gynoecium development. Plant J. 2000;21:419-29 pubmed
..resulting from a reduction of transcript levels of the Arabidopsis SHAGGY-related protein kinase genes AtSK11(ASKalpha) and AtSK12(ASKgamma)...
Han L, Mason M, Risseeuw E, Crosby W, Somers D. Formation of an SCF(ZTL) complex is required for proper regulation of circadian timing. Plant J. 2004;40:291-301 pubmed
..Taken together, our data establish SCFZTL as an essential SCF class E3 ligase controlling circadian period in plants. ..